Results 41 to 50 of about 951 (168)
Inhibitory activities of ethanol extracts from seven fermented soybean products, including douchi, sufu, stinky tofu, to acetylcholinesterase were determined, and crude extract from Yongchuan douchi, which showed the strongest inhibitory effect, was ...
Yunbin Zhang +4 more
doaj +1 more source
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang +3 more
wiley +1 more source
Menaquinone (MK) has an important role in human metabolism as an essential vitamin (VK2), which is mainly produced through the fermentation of microorganisms. MK8(H2) was identified to be the main menaquinone from Rhodococcus sp.
Yashu Chen +7 more
doaj +1 more source
Abstract High performance countercurrent membrane purification (HPCMP) has emerged as a promising diffusive separation strategy for the purification of recombinant proteins and monoclonal antibodies (mAbs). However, prior studies employed dialysis membranes, which are designed for diffusive separations but have not been validated for biopharmaceutical ...
Aylin Mohammadzadehmarandi +8 more
wiley +1 more source
Importance of Downstream Processing of Natural Astaxanthin for Pharmaceutical Application
Astaxanthin (ASX) is a xanthophyll pigment considered as a nutraceutical with high antioxidant activity. Several clinical trials have shown the multiple health benefits of this molecule; therefore, it has various pharmaceutical industry applications ...
Lucio Rodríguez-Sifuentes +3 more
doaj +1 more source
This review highlights green recovery, purification, stabilisation, bioavailability, health relevance, and novel food applications of anthocyanins from natural and agro‐industrial sources. ABSTRACT Anthocyanins are water‐soluble natural pigments and multifunctional food ingredients that support clean‐label colour, antioxidant activity, and value‐added ...
Chandan Kumar Sahu +4 more
wiley +1 more source
High speed countercurrent chromatography has unique advantages in resolving the bottleneck of separation and purification of active ingredients in the field of biomedicine, such as no irreversible adsorption, high sample recovery and good tolerance ...
Guofu YIN +4 more
doaj
Urtica laetevirens Maxim. is used extensively in traditional Chinese medicine (TCM) for its potent antioxidative properties. In this study, three antioxidants were purified from U. laetevirens. using HSCCC guided by online DPPH-HPLC analysis.
Aijing Li +9 more
doaj +1 more source
Toward Robust Optimal Control of Chromatographic Separation Processes With Controlled Flow Reversal
ABSTRACT Column liquid chromatography is an important technique applied in the production of biopharmaceuticals, specifically for the separation of biological macromolecules such as proteins. When setting up process conditions, it is crucial that the purity of the product is sufficiently high, even in the presence of perturbations in the process ...
Dominik H. Cebulla +2 more
wiley +1 more source
Rice false smut is an emerging plant disease worldwide. Ustiloxin A (UstA) is the major mycotoxin found in rice false smut balls, which are fungal colonies in rice florets. In this study, a new method consisting of macroporous resin column chromatography
Gang Wang +6 more
doaj +1 more source

