Results 51 to 60 of about 15,904,426 (181)

Importance of Downstream Processing of Natural Astaxanthin for Pharmaceutical Application

Frontiers in Chemical Engineering, 2021
Astaxanthin (ASX) is a xanthophyll pigment considered as a nutraceutical with high antioxidant activity. Several clinical trials have shown the multiple health benefits of this molecule; therefore, it has various pharmaceutical industry applications ...
Lucio Rodríguez-Sifuentes, Jolanta Elzbieta Marszalek, Gerardo Hernández-Carbajal, Cristina Chuck-Hernández   +3 more
doaj   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

Biotechnology and Bioengineering, Volume 123, Issue 9, Page 2303-2311, September 2026.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang, Amin Javidanbardan, Ali Behboudi, Andrew L. Zydney   +3 more
wiley   +1 more source

Structure Design and Topology Optimization of Planet Carrier of High Speed Countercurrent Chromatograph

工程科学与技术, 2020
High speed countercurrent chromatography has unique advantages in resolving the bottleneck of separation and purification of active ingredients in the field of biomedicine, such as no irreversible adsorption, high sample recovery and good tolerance ...
Guofu YIN, Jianfeng CHEN, Haijun CHEN, Yuxuan WU, Haisong LIU   +4 more
doaj  

Target-Guided Isolation and Purification of Antioxidants from Urtica laetevirens Maxim. by HSCCC Combined with Online DPPH-HPLC Analysis

Molecules, 2023
Urtica laetevirens Maxim. is used extensively in traditional Chinese medicine (TCM) for its potent antioxidative properties. In this study, three antioxidants were purified from U. laetevirens. using HSCCC guided by online DPPH-HPLC analysis.
Aijing Li, Mencuo La, Huichun Wang, Jianzhong Zhao, Yao Wang, Ruisha Mian, Fangfang He, Yuhan Wang, Tingqin Yang, Denglang Zou   +9 more
doaj   +1 more source

Extraction and purification of ustiloxin A from rice false smut balls by a combination of macroporous resin and high-speed countercurrent chromatography

Food Production, Processing and Nutrition, 2020
Rice false smut is an emerging plant disease worldwide. Ustiloxin A (UstA) is the major mycotoxin found in rice false smut balls, which are fungal colonies in rice florets. In this study, a new method consisting of macroporous resin column chromatography
Gang Wang, Dan He, Fengchun Zhao, Junqiang Hu, Yin-Won Lee, Jianrong Shi, Jianhong Xu   +6 more
doaj   +1 more source

Anti-Inflammatory Effect of Ebractenoid F, a Major Active Compound of Euphorbia ebracteolata Hayata, through Inhibition of Nuclear Factor-κB Activation

Plants, 2023
Euphorbia ebracteolata Hayata (Euphorbiaceae family) is a perennial plant that is widely distributed in Korea, Japan, and China. Its roots contain bioactive diterpenes that have anti-inflammatory properties.
Jaemoo Chun, Sang Yeon Mah, Yeong Shik Kim   +2 more
doaj   +1 more source

Toward Robust Optimal Control of Chromatographic Separation Processes With Controlled Flow Reversal

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 3, September 2026.
ABSTRACT Column liquid chromatography is an important technique applied in the production of biopharmaceuticals, specifically for the separation of biological macromolecules such as proteins. When setting up process conditions, it is crucial that the purity of the product is sufficiently high, even in the presence of perturbations in the process ...
Dominik H. Cebulla, Christian Kirches, Andreas Potschka   +2 more
wiley   +1 more source

Separation and Purification of Lycium barbarum Polysaccharides in Neuroinflammation by High-speed Countercurrent Chromatography

Shipin gongye ke-ji
Objective: This study constructed a novel method for the separation and purification of polysaccharides from Lycium barbarum polysaccharide (LBPs) by high-speed countercurrent chromatography with aqueoust two-phase system, and investigated its effect on ...
Gaofeng HAO, Yu CAO, Ning ZHAO, Jianfei LIU, Duolong DI   +4 more
doaj   +1 more source

Separation of Seven Polyphenols from the Rhizome of Smilax glabra by Offline Two Dimension Recycling HSCCC with Extrusion Mode

Molecules, 2018
An offline two-dimensional recycling high-speed countercurrent chromatography (2D R-HSCCC) strategy with extrusion mode was developed for isolating polyphenols from the rhizome of Smilax glabra.
Wei Guo, Hongjing Dong, Daijie Wang, Bin Yang, Xiao Wang, Luqi Huang   +5 more
doaj   +1 more source

Understanding Mass Spectrometry: From Ion Generation to Spectral Interpretation

Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT This tutorial provides a structured introduction to mass spectrometry (MS), with particular emphasis on electrospray ionization (ESI)–based measurements. It is intended to support researchers from chemistry and related disciplines in developing a coherent understanding of MS principles, instrumentation, and data interpretation.
Arnold Steckel, Dávid Papp, Gitta Schlosser   +2 more
wiley   +1 more source