Results 91 to 100 of about 696,698 (308)

High-speed visualization of metal oxide precursor in thermal plasma flow during nanoparticle formation

open access: yesJournal of Fluid Science and Technology, 2019
The objective of the present study is to understand formation mechanism of metal oxide nanoparticles in thermal plasma. High-speed camera technique with appropriate band-pass filters was applied to visualize the precursors of the metal oxide ...
Manabu TANAKA   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

High-sensitivity high-speed compressive spectrometer for Raman imaging

open access: yes, 2018
Compressive Raman is a recent framework that allows for large data compression of microspectroscopy during its measurement. Because of its inherent multiplexing architecture, it has shown imaging speeds considerably higher than conventional Raman ...
Herve Rigneault (5317358)   +5 more
core   +1 more source

FluorATOM: high-throughput imaging flow cytometry for synchronized biophysical and biomolecular phenotyping

open access: yes, 2020
Multiplexed asymmetric-detection time-stretch optical microscopy (multi-ATOM) has recently been developed to enable high-throughput quantitative phase imaging flow cytometry, from which single-cell biophysical properties can be measured at large scale ...
Kwong, A   +7 more
core   +1 more source

Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light. [PDF]

open access: yes, 2012
Fluorescence imaging is one of the most important research tools in biomedical sciences. However, scattering of light severely impedes imaging of thick biological samples beyond the ballistic regime.
Wang, Ying Min   +4 more
core   +1 more source

When superhydrophobicity can be a drag: ventilated cavitation and splashing effects in hydrofoil and speed-boat models tests

open access: yes, 2021
Superhydrophobic surfaces are expected to reduce the hydrodynamic drag on marine vessels due to the lubrication effects of the naturally sustained thin air-layer plastron.
Vakarelski, Ivan Uriev   +3 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A novel high-speed digital imaging system for assessing vocal fold vibration

open access: yes, 2014
Observing vocal fold vibration is essential when investigating the causes of hoarseness of voice and determining the appropriate treatment. However, in Japan, it is difficult at present to obtain commercial high-speed digital imaging (HSDI) systems for ...
Kaneko, Kenichi   +3 more
core  

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