Results 101 to 110 of about 17,316,343 (262)

Development of a novel powder sheets printing process towards the next generation of additive manufacturing: the role of laser defocusing

open access: yesVirtual and Physical Prototyping
To address safety and labour-intensive challenges in laser powder bed fusion, a novel Metal Additive Manufacturing using Powder Sheets (MAPS) method is employed.
Wenyou Zhang   +15 more
doaj   +1 more source

High-speed imaging reveals the bimodal nature of dense core vesicle exocytosis. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Zhang P, Rumschitzki D, Edwards RH.
europepmc   +1 more source

Parallelized compressive spontaneous Raman imaging via SPAD arrays (Conference Presentation)

open access: yes
Compressive Raman imaging has emerged as a promising technique to speed up chemical imaging by compressing the data during acquisition. Yet, current scanning imaging speed is fundamentally limited by the sensors pixel dwell times of at best 1 µs.
Gentner, Clémence   +4 more
core   +1 more source

FluorATOM: high-throughput imaging flow cytometry for synchronized biophysical and biomolecular phenotyping

open access: yes, 2020
Multiplexed asymmetric-detection time-stretch optical microscopy (multi-ATOM) has recently been developed to enable high-throughput quantitative phase imaging flow cytometry, from which single-cell biophysical properties can be measured at large scale ...
Kwong, A   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

High-throughput single-cell imaging by multi-modal FACED microscopy

open access: yes, 2019
We demonstrate a high-throughput multimodal imaging flow cytometry platform based on a recently developed all-optical laser scanning technique dubbed free-space angular chirped enhanced delay (FACED).
Wong, KKY   +4 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

High-speed imaging of light-induced photoreceptor microsaccades in compound eyes. [PDF]

open access: yesCommun Biol, 2022
Kemppainen J   +3 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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