Results 51 to 60 of about 100,949 (247)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Optimization Based High-Speed Railway Train Rescheduling with Speed Restriction

open access: yesDiscrete Dynamics in Nature and Society, 2014
A decision support framework with four components is proposed for high-speed railway timetable rescheduling in case of speed restriction. The first module provides the speed restriction information.
Li Wang   +4 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg

open access: yesJournal of Materials Research and Technology
Selective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue   +5 more
doaj   +1 more source

Evaluation of Ankara – Istanbul high speed train project [PDF]

open access: yesTransport, 2007
Many countries have been carrying out some changes in their transportation policies for the sake of environmental and economical considerations. These circumstances have also affected Turkey to change the national transportation policies.
A. P. Akgungor, A. Demirel
doaj  

Location-Fair Beamforming for High Speed Railway Communication Systems

open access: yesIEEE Access, 2018
In this paper, transmission scheme for the base station with a large number of antennas in the high-speed train (HST) networks in the presence of Doppler shift is considered.
Ximei Liu, Deli Qiao
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Dynamic Control of High-speed Train Following Operation

open access: yesPromet (Zagreb), 2014
Both safety and efficiency should be considered in high-speed train following control. The real-time calculation of dynamic safety following distance is used by the following train to understand the quality of its own following behavior.
Deng Pan, Yingping Zheng
doaj   +1 more source

Home - About - Disclaimer - Privacy