Results 51 to 60 of about 108,599 (296)

Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg

open access: yesJournal of Materials Research and Technology
Selective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue   +5 more
doaj   +1 more source

Location-Fair Beamforming for High Speed Railway Communication Systems

open access: yesIEEE Access, 2018
In this paper, transmission scheme for the base station with a large number of antennas in the high-speed train (HST) networks in the presence of Doppler shift is considered.
Ximei Liu, Deli Qiao
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Evaluation of Ankara – Istanbul high speed train project [PDF]

open access: yesTransport, 2007
Many countries have been carrying out some changes in their transportation policies for the sake of environmental and economical considerations. These circumstances have also affected Turkey to change the national transportation policies.
A. P. Akgungor, A. Demirel
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Research on the Train Surface Pressure Characteristics in Passing through Tunnels at Speeds of 400 km/h and above

open access: yesChengshi guidao jiaotong yanjiu
[Objective] In order to ensure the running safety of trains with a speed of 400 km/h and above when passing through tunnels and improve the passenger ride comfort, it is necessary to adopt the numerical simulation method to study the characteristics of ...
HU Yingcan   +4 more
doaj   +1 more source

Dynamic Control of High-speed Train Following Operation

open access: yesPromet (Zagreb), 2014
Both safety and efficiency should be considered in high-speed train following control. The real-time calculation of dynamic safety following distance is used by the following train to understand the quality of its own following behavior.
Deng Pan, Yingping Zheng
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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