Results 71 to 80 of about 180,713 (315)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Code for the high-speed railway network dataset from train operation records and weather data

, 2021
Code for the generation of the high-speed railway network ...
Yunhao Chong, Jiqiang Liu, Nan Wang, Lingyun Lu, Yunjuan Peng, Daohua Wu, Chenyue Du, Hongwei Wang, Jintao Liu, Hailong Zhang, Yumei Zhang, Dalin Zhang, Yi Xu   +12 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Optimization Based High-Speed Railway Train Rescheduling with Speed Restriction

Discrete Dynamics in Nature and Society, 2014
A decision support framework with four components is proposed for high-speed railway timetable rescheduling in case of speed restriction. The first module provides the speed restriction information.
Li Wang, Wenting Mo, Yong Qin, Fei Dou, Limin Jia   +4 more
doaj   +1 more source

Location-Fair Beamforming for High Speed Railway Communication Systems

IEEE Access, 2018
In this paper, transmission scheme for the base station with a large number of antennas in the high-speed train (HST) networks in the presence of Doppler shift is considered.
Ximei Liu, Deli Qiao
doaj   +1 more source

High speed short range optical wireless ground-to-train communications

, 2010
There is a huge demand for seamless high-speed communications in fast moving trains. People want broadband services while on board as in their home or in the workplace.
Ghassemlooy, Zabih, Paudel, Rupak, Rajbhandari, Sujan, Le Minh, Hoa   +3 more
core  

Considerations on Active Control of Crosswind Stability of Railway Vehicles

, 2013
The DLR research project Next Generation Train deals with concepts, methods and technologies for a very high-speed train in double deck configuration and light-weight design.
Kurzeck, Bernhard, Bünte, Tilman, Loose, Sigfried, Heckmann, Andreas   +3 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg

Journal of Materials Research and Technology
Selective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue, Xu Zhang, Dongming Li, Zhuofeng Li, Zhaoyi Wang, Bingzhi Chen   +5 more
doaj   +1 more source

Evaluation of Ankara – Istanbul high speed train project [PDF]

Transport, 2007
Many countries have been carrying out some changes in their transportation policies for the sake of environmental and economical considerations. These circumstances have also affected Turkey to change the national transportation policies.
A. P. Akgungor, A. Demirel
doaj