Results 71 to 80 of about 867,475 (306)

Advanced Diagnostics of Position Sensors for the Actuation Systems of High-Speed Tilting Trains [PDF]

open access: yes, 2010
Trains tilting permits a train to travel at a high speed while maintaining an acceptable passenger ride quality with respect to the lateral acceleration, and the consequent lateral force, received by the passengers when the train travels on a curved ...
Jacazio, Giovanni   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Designing a crisis communication plan in the Chinese Ministry of Railways [PDF]

open access: yes, 2013
This project presents a crisis communication plan for the Chinese Ministry of Railways, as Wenzhou high-speed train crash incident is the background.
Xiong, Shengya
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Crew Rostering for the High Speed Train [PDF]

open access: yes
At the time of writing we entered the final stage of implementing the crew rostering system Harmony CDR to facilitate the planning of catering crews on board of the Thalys, the High Speed Train connecting Paris, Cologne, Brussels, Amsterdam, and Geneva ...
Lentink, R.M., Odijk, M.A., Rijn, E. van
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg

open access: yesJournal of Materials Research and Technology
Selective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue   +5 more
doaj   +1 more source

Optimization Based High-Speed Railway Train Rescheduling with Speed Restriction

open access: yesDiscrete Dynamics in Nature and Society, 2014
A decision support framework with four components is proposed for high-speed railway timetable rescheduling in case of speed restriction. The first module provides the speed restriction information.
Li Wang   +4 more
doaj   +1 more source

Location-Fair Beamforming for High Speed Railway Communication Systems

open access: yesIEEE Access, 2018
In this paper, transmission scheme for the base station with a large number of antennas in the high-speed train (HST) networks in the presence of Doppler shift is considered.
Ximei Liu, Deli Qiao
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy