Results 51 to 60 of about 180,713 (315)

Mechanical properties and energy absorption of CoCrNi functionally graded TPMS cellular structures

Journal of Materials Research and Technology
Functionally gradient triply periodic minimal surface (TPMS) structures are found widespread applications in fields such as aerospace and defense engineering, owing to flexible modulation of lightweight and energy-absorbing properties.
Zhaoyi Wang, Junxian Zhou, Yunzhuo Lu, Dongming Li, Deyu Yue, Xu Zhang, Bingzhi Chen   +6 more
doaj   +1 more source

Research on speed control of high-speed train based on multi-point model [PDF]

Archives of Transport, 2019
The traditional train speed control research regards the train as a particle, ignoring the length of the train and the interaction force between carriages.
Tao Hou, Yang-yang Guo, Hong-xia Niu
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Fatigue performance of bogie weld roots: Failure analysis and numerical modeling

Results in Engineering
In engineering practice, accurately identifying root failure mechanisms and quantitatively evaluating fatigue performance improvements in the absence of load spectrum conditions remains a challenge.
Shaoze Zhou, Zhen Zhang, Desong Meng, Jun Zhang   +3 more
doaj   +1 more source

Influence of Nose-slenderness Ratio on Air Pressure Pulse of High-speed Trains Passing Each Other

Journal of Applied Science and Engineering, 2021
The strength of side windows, the stability of train operation, and the comfort of passengers will be affected by air pressure fluctuations when the high-speed train meets.
Lin Ma, Zihao Xie, Weiyu Chen, ZhenfengWu   +3 more
doaj   +1 more source

Research on influence of the type of cross wind field on the aerodynamic performance of a high-speed train

, 2012
Characteristic of cross wind field, such as uniform wind and lower atmospheric boundary layer wind, have directly influence on the operation safety of high-speed train which running in cross wind environment.
Fang Y, Yang GW(杨国伟), Xi YH, Mao J
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Laser additive manufacturing of hierarchical multifunctional chiral metamaterial with distinguished damage-resistance and low-frequency broadband sound-absorption capabilities

Materials & Design
Traditional materials or advanced artificially engineered metamaterials are incapable of effectively addressing the simultaneous challenges of impact energy hazards and low-frequency noise.
Xi Wang, Ruixian Qin, Jiaming Lu, Minghao Huang, Xu Zhang, Bingzhi Chen   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Sound and mechanical impedance behaviors observed in multifunctional modular bio-inspired lattice metamaterials

Materials & Design
Noise and impact hazards are ubiquitous in engineering applications, creating an urgent demand for multifunctional materials capable of absorbing both acoustic and stress wave energy.
Shiyi Wang, Xi Wang, Ruixian Qin, Qijian Li, Bingzhi Chen   +4 more
doaj   +1 more source