Results 71 to 80 of about 108,599 (296)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Design and analysis of biomimetic nested lattice structures based on additive manufacturing

open access: yesAlexandria Engineering Journal
There are various hierarchical structures in nature, such as the double-layer wings of a dragonfly, which possess enhanced mechanical properties while also being lightweight.
Dongming Li   +3 more
doaj   +1 more source

A System-Level Performance Evaluation for a 5G System under a Leaky Coaxial Cable MIMO Channel for High-Speed Trains in the Railway Tunnel [PDF]

open access: gold, 2022
Penghui Liu   +7 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Innovation and Development of High-speed Railway in China

open access: yes机车电传动, 2010
This paper introduced the construction plan of China’s high-speed railway and described nine key technologies and ten supporting techniques of high speed train. The basic model of China high speed train has been given.
张卫华, 王伯铭
doaj  

The high-speed train and its spatial effects [PDF]

open access: yesInvestigaciones Regionales - Journal of Regional Research, 2004
This paper analyses the high-speed train from a spatial point of view. The basic characteristics of this transportation mode,the evolution of high-speed networks in several countries and the building of a trans-European high-speed railway network are ...
Javier Gutiérrez Puebla
doaj  

Model Of High-Speed Train Energy Consumption

open access: yes, 2013
In the hardening energy context, the transport sector which constitutes a large worldwide energy demand has to be improving for decrease energy demand and global warming impacts. In a controversial situation where subsists an increasing demand for long-distance and high-speed travels, high-speed trains offer many advantages, as consuming significantly ...
Vandanjon, Pierre Olivier   +3 more
openaire   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

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