Results 21 to 30 of about 19,813 (258)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Education, 2021 Multistage test (MST) designs promise efficient student ability estimates, an indispensable asset for individual diagnostics in high-stakes educational assessments.
Laura A. Helbling +2 more
doaj +1 more source
Washback Effect of TEFL MA Exam on Iranian Lecturers’ Classroom Activities [PDF]
Applied Research on English Language, 2018 Washback refers to the effect of testing on teaching and learning. The university entrance exam for Iranian MA candidates of Teaching English as a Foreign Language (hereinafter TEFL MA UEE) is a nationwide high-stakes test administered every year, and ...
Azadeh Pakzad, Hadi Salehi
doaj +1 more source
Journal of Educational Sciences Research, 2015 Egitim genel olarak bir ogrenme surecidir ve bu surecte bireylere bilgiyi yasamda kullanabilme becerisinin ogretilmesi amaclanmaktadir. Bilgiyi yasamda kullanabilen bireyler yetistirmenin onemini anlayan ulkeler egitim kademelerindeki niteligi arttirma cabasi icerisinde yer almaktadir. Orgun egitim kurumlarinda verilen egitimin niteligini belirlemek ve
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
High-stakes test anxiety among Taiwanese adolescents: a longitudinal study
Cogent EducationThis study examined changes of test anxiety under the reform of the examination system in Taiwan. We sampled 46,361 Grade 9 students in Taiwan for 9 consecutive years starting from 2011 to collect data on their test anxiety, cram school attendance ...
Tzu-Yang Chao +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Computers and Education Open, 2021 The onset of the COVID-19 pandemic brought with it the closure of many bricks-and-mortar testing centres and a concomitant move to the remote (online) proctoring of many credentialing exams that were scheduled to take place throughout 2020.
Gemma Cherry +4 more
doaj +1 more source