Results 41 to 50 of about 19,813 (258)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Testing: A Systemic Functional View of High Stakes Test Preparation Materials
Colombian Applied Linguistics Journal, 2011 Los docentes de inglés usan con frecuencia materiales de preparación para ayudarles a los aprendices a tomar exámenes estandarizados que midan su conocimiento en esta lengua. Este estudio usa herramientas de la lingüística sistémica funcional (SFL), para
Joshua Schulze
doaj
Journal of IntelligenceAlthough cognitive ability tests are among the best predictors of job and training performance, their acceptance among applicants is limited. However, with the current talent shortage, applicant reactions to assessments have become increasingly important.
Marie L. Ohlms, Klaus G. Melchers
doaj +1 more source
On the Construct Validity of the Reading Section of the University of Tehran English Proficiency Test [PDF]
Journal of English Language Teaching and Learning, 2011 University of Tehran administers a test known as The University of Tehran English Proficiency Test (the UTEPT) to PhD candidates on a yearly basis. By definition, the test can be considered a high-stakes one. The validity of high stakes tests needs to be
Mohammad Salehi
doaj
RECONSIDERING THE IMPACT OF HIGH‐STAKES TESTING [PDF]
ETS Research Report Series, 2003 ABSTRACTOver the last 15 years, many states have implemented high‐stakes tests as part of an effort to strengthen accountability for schools, teachers, and students. Predictably, there has been vigorous disagreement regarding the contributions of such policies to increasing test scores and, more importantly, to improving student learning.
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
L2 pragmatics underrepresentation as a washback mechanism in EFL contexts: Linking test-design features to high-stakes test use [PDF]
Teaching English Language, 2014 Considering the status of 'washback' in validity theory and research, Messick warns that, to establish test validity, one should not rely merely on washback, with all its complexity, but should instead probe test design properties (i.e., authenticity and
Azizullah Mirzaei +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source