Results 41 to 50 of about 21,047,093 (292)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Bioscience Students in Physics Courses with Higher Test Anxiety Have Lower Grades on High-Stakes Assessments and Women Report More Test Anxiety than Men

Education Sciences
Test anxiety is beginning to be recognized as a significant factor affecting student performance in science, technology, engineering, and mathematics (STEM) courses, potentially contributing to gender inequity within these fields.
Alysa Malespina, Fargol Seifollahi, Chandralekha Singh   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Source of Lake Wobegon [updated]

Nonpartisan Education Review, 2010
John J. Cannell's late 1980's "Lake Wobegon" reports suggested widespread deliberateeducator manipulation of norm-referenced standardized test (NRT) administrations and results,resulting in artificial test score gains.
Richard P. Phelps
doaj  

Examining the Myth of Accountability, High-Stakes Testing, and the Achievement Gap

Journal of Family Strengths, 2018
In this article we outline how notions of accountability and the achievement gap have relied upon the massive expansion of high-stakes exams in our nation’s schools. Texas-style test and punish accountability manifested in various ways within schools and
Julian Vasquez Heilig, T. Jameson Brewer, Jimmy Ojeda Pedraza   +2 more
doaj   +1 more source

High Stake Tests

Journal of Educational Sciences Research, 2015
Egitim genel olarak bir ogrenme surecidir ve bu surecte bireylere bilgiyi yasamda kullanabilme becerisinin ogretilmesi amaclanmaktadir. Bilgiyi yasamda kullanabilen bireyler yetistirmenin onemini anlayan ulkeler egitim kademelerindeki niteligi arttirma cabasi icerisinde yer almaktadir. Orgun egitim kurumlarinda verilen egitimin niteligini belirlemek ve
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Testing: A Systemic Functional View of High Stakes Test Preparation Materials

Colombian Applied Linguistics Journal, 2011
Los docentes de inglés usan con frecuencia materiales de preparación para ayudarles a los aprendices a tomar exámenes estandarizados que midan su conocimiento en esta lengua. Este estudio usa herramientas de la lingüística sistémica funcional (SFL), para
Joshua Schulze
doaj  

Do Applicant Reactions to Gamified Cognitive Ability Tests Differ Between High- Versus Low-Stakes Settings?

Journal of Intelligence
Although cognitive ability tests are among the best predictors of job and training performance, their acceptance among applicants is limited. However, with the current talent shortage, applicant reactions to assessments have become increasingly important.
Marie L. Ohlms, Klaus G. Melchers
doaj   +1 more source