Results 61 to 70 of about 249,593 (301)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Testing: A Systemic Functional View of High Stakes Test Preparation Materials

open access: yesColombian Applied Linguistics Journal, 2011
Los docentes de inglés usan con frecuencia materiales de preparación para ayudarles a los aprendices a tomar exámenes estandarizados que midan su conocimiento en esta lengua. Este estudio usa herramientas de la lingüística sistémica funcional (SFL), para
Joshua Schulze
doaj  

Do Applicant Reactions to Gamified Cognitive Ability Tests Differ Between High- Versus Low-Stakes Settings?

open access: yesJournal of Intelligence
Although cognitive ability tests are among the best predictors of job and training performance, their acceptance among applicants is limited. However, with the current talent shortage, applicant reactions to assessments have become increasingly important.
Marie L. Ohlms, Klaus G. Melchers
doaj   +1 more source

On the Construct Validity of the Reading Section of the University of Tehran English Proficiency Test [PDF]

open access: yesJournal of English Language Teaching and Learning, 2011
University of Tehran administers a test known as The University of Tehran English Proficiency Test (the UTEPT) to PhD candidates on a yearly basis. By definition, the test can be considered a high-stakes one. The validity of high stakes tests needs to be
Mohammad Salehi
doaj  

RECONSIDERING THE IMPACT OF HIGH‐STAKES TESTING [PDF]

open access: yesETS Research Report Series, 2003
ABSTRACTOver the last 15 years, many states have implemented high‐stakes tests as part of an effort to strengthen accountability for schools, teachers, and students. Predictably, there has been vigorous disagreement regarding the contributions of such policies to increasing test scores and, more importantly, to improving student learning.
openaire   +3 more sources

LEXTALE_CH: A quick, character-based proficiency test for Mandarin Chinese [PDF]

open access: yes, 2018
Research in second language acquisition suggests that objective performance-based assessments may provide more reliable and valid measures of second language proficiency than subjective self-ratings. To measure proficiency in English as a second language,
Chan, I. Lei, Chang, Charles B.
core  

Literacy assessment practices: Moving from standardised to ecologically valid assessments in secondary schools [PDF]

open access: yes, 2007
SSLI test protocol data revealed the dominance of 'central' literacy measures and 'local' subject-specific measures aligned to institutional requirements, curriculum and national examination content.
Whitehead, David
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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