Results 121 to 130 of about 15,621,385 (284)

Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies. [PDF]

open access: yes, 2015
The ability to identify regions of the genome inherited with a dominant trait in one or more families has become increasingly valuable with the wide availability of high throughput sequencing technology.
Neild, GH   +6 more
core   +3 more sources

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

open access: yesAdvanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma   +22 more
wiley   +1 more source

Utilization of high throughput genome sequencing technology for large scale single nucleotide polymorphism discovery in red deer and Canadian elk [PDF]

open access: yes, 2015
ABSTRACT Deer farming is a significant international industry. For genetic improvement, using genomic tools, an ordered array of DNA variants and associated flanking sequence across the genome is required. This work reports a comparative assembly of the deer genome and subsequent DNA variant identification.
Brauning, Rudiger   +8 more
openaire   +1 more source

Metagenome sequencing-based strain-level and functional characterization of supragingival microbiome associated with dental caries in children

open access: yesJournal of Oral Microbiology, 2019
Studies of the microbiome associated with dental caries have largely relied on 16S rRNA sequence analysis, which is associated with PCR biases, low taxonomic resolution, and inability to accurately study functions.
Nezar Noor Al-Hebshi   +8 more
doaj   +1 more source

Development of methods for the analysis of deep sequencing data; applications to the discovery of functions of RNA-binding proteins [PDF]

open access: yes, 2014
With the recent advances in nucleotide sequencing technologies, it became easy to generate tens of millions of reads with genome- or transcriptome-wide distribution with reduced cost and high accuracy.
Bilen, Biter
core   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

Additional file 6: of Uncommon nucleotide excision repair phenotypes revealed by targeted high-throughput sequencing

open access: yes, 2016
Clinical pictures and brain MRI of patients #16 (mutated in ERCC5(XPG)). Sagittal T1 and axial T2-Flair (PPTX 970 kb)
Calmels, Nadège   +28 more
openaire   +1 more source

Revolutionising Agricultural Sustainability: New ‘Furrow Tillage’ can Mitigate Short‐Term Soil‐to‐Atmosphere CO2 Flux and Promote Soil‐Plant‐Microbe Health

open access: yesAdvanced Science, EarlyView.
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar   +10 more
wiley   +1 more source

Genetic landscape of myelodysplastic syndrome and its prognostic relevance: a study from Pakistan

open access: yesJournal of the Pakistan Medical Association
Objective: To determine the genetic landscape of myelodysplastic syndrome patients, and to evaluate the impact of gene mutations on disease prognosis and overall survival.
Alia Waheed   +5 more
doaj   +1 more source

Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns [PDF]

open access: yes, 2012
Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular
Michael Bunce   +43 more
core   +2 more sources

Home - About - Disclaimer - Privacy