Results 181 to 190 of about 229,759 (254)

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

ELECTROPHORESIS, EarlyView.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht, Cari E. Sänger ‐ van de Griend   +1 more
wiley   +1 more source

FPGA-based accelerator for adaptive banded event alignment in nanopore sequencing data analysis. [PDF]

BMC Bioinformatics
Feng Y, Li Z, Gudukbay Akbulut G, Narayanan V, Kandemir MT, Das CR.   +5 more
europepmc   +1 more source

A SNaPshot Assay for Epigenetic Age Prediction of Costal Cartilage

ELECTROPHORESIS, EarlyView.
ABSTRACT Estimating age at death narrows the pool of potential donors in mass disasters and criminal investigations. In this study, we developed a capillary electrophoresis‐based SNaPshot assay for age prediction of costal cartilage and used it to analyze DNA methylation at 11 CpG sites across six genes in 136 samples from deceased Koreans aged 28–84 ...
Ju Yeon Jung, Yeon Woo Song, Kyu‐Sik Jeong, Hyun‐Chul Park, Moon Hyun So, Hwan Young Lee   +5 more
wiley   +1 more source

EasyDIVER + : An Advanced Tool for Analyzing High Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Amino Acids. [PDF]

J Mol Evol
Blanco C, Tee A, Sharma P, Newton MS, Lee KH, Erickson SE, Seelig B, Chen IA.   +7 more
europepmc   +1 more source

Utilization of high throughput genome sequencing technology for large scale single nucleotide polymorphism discovery in red deer and Canadian elk

, 2016
Rüdiger Bräuning, P. J. Fisher, Alan McCulloch, Russell J Smithies, James F Ward, Matthew J. Bixley, Cindy Lawley, Suzanne J. Rowe, John C. McEwan   +8 more
openalex   +2 more sources

High-throughput single nucleotide polymorphism (SNP) identification and mapping in the sesame (Sesamum indicum L.) genome with genotyping by sequencing (GBS) analysis [PDF]

, 2016
Ayşe Özgür Uncu, Anne Frary, Petr Karlovský, Sami Doğanlar   +3 more
openalex   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

High-throughput Kinetics using capillary Electrophoresis and Robotics (HiKER) platform used to study T7, T3, and Sp6 RNA polymerase misincorporation. [PDF]

PLoS One
Carter ZI, O'Brien WB, Lund S, Gardner AF.   +3 more
europepmc   +1 more source

Long-read metagenomics gives a more accurate insight into the microbiota of long-ripened gouda cheeses. [PDF]

Front Microbiol
Decadt H, Díaz-Muñoz C, Vermote L, Pradal I, De Vuyst L, Weckx S.   +5 more
europepmc   +1 more source

A splendid banana enigma: Phylogenomic assessment of Vietnamese Musa splendida and Musa viridis populations shows that they are conspecific. [PDF]

PLoS One
Bawin Y, Mertens A, de Backer S, Vu DT, Le LT, Vu TD, Janssens SB.   +6 more
europepmc   +1 more source