Results 181 to 190 of about 149,249 (267)

Intranuclear paraspeckle‐circular RNA TACC3 assembly forms RNA‐DNA hybrids to facilitate MASH‐related hepatocellular carcinoma growth in an m6A‐dependent manner

Cancer Communications, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is anticipated to become the leading cause of hepatocellular carcinoma (HCC). Accumulating evidence indicates that N6‐methyladenosine (m6A)‐modified circular RNAs (circRNAs) play key roles in tumor malignant progression.
Jingbo Fu, Yanping Wei, Yun Yang, Xinwei Yang, Tao Ouyang, Xianming Wang, Shuzhen Chen, Zenglin Liu, Yu Su, Jing Fu, Miao Yu, Haihua Qian, Hao Song, Shuo Xu, Ru Zhao, Xue Jiang, Yunfei Huo, Man Zhang, Pinhua Yang, Zhao Yang, Kui Wang, Liang Li, Hongyang Wang   +22 more
wiley   +1 more source

Bacterial Systematic Genetics and Integrated Multi-Omics: Beyond Static Genomics Toward Predictive Models. [PDF]

Int J Mol Sci
Sakaguchi T, Irifune Y, Kamada R, Sakaguchi K.   +3 more
europepmc   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Craft: a machine learning approach to dengue subtyping. [PDF]

Bioinform Adv
van Zyl DJ, Dunaiski M, Tegally H, Baxter C, de Oliveira T, Xavier JS, INFORM Africa Research Study Group .   +6 more
europepmc   +1 more source

Biotechnological Potential of Seaweeds from Bahia, Brazil: Metabolomic insights, Photoprotection and Antioxidant Activity

Chemistry &Biodiversity, EarlyView.
Chemical profile, photoprotective, and antioxidant potential of Padina sp., Caulerpa sertularioides, and Solieria filiformis collected in Bahia, Brazil. ABSTRACT Seaweeds have wide biotechnological applications. This study evaluated the chemical profile, photoprotective, and antioxidant potential of Padina sp., Caulerpa sertularioides, and Solieria ...
Keila Almeida Santana, Isadora de Jesus da Silva, Victor Pena Ribeiro, José Marcos de Castro Nunes, Hosana Maria Debonsi, Ian Castro‐Gamboa, Lorena Rigo Gaspar, Gustavo Souza dos Santos, Aníbal de Freitas Santos Júnior   +8 more
wiley   +1 more source

SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data. [PDF]

BMC Bioinformatics
Wang J, Sun S, Zhang Y, Huang N, Yang C, Gao Y, Wang X, Ju Z, Jiang Q, Xiao Y, Wei X, Liu W, Huang J.   +12 more
europepmc   +1 more source

A Route to Design Novel Functional Peptides by Applying a Denoising Diffusional Model to mRNA Display Libraries

ChemBioChem, EarlyView.
A denoising diffusional implicit model (DDIM) is trained using sequencing data from mRNA display selections to generate novel peptide sequences. This approach integrates experimental and computational methods to efficiently design peptides with enhanced binding properties, accelerating ligand discovery.
Pearl Qi, Yash Pragnesh Gandhi, Kexin Zheng, Farzad Jalali‐Yazdi, Justin N. Ong, Terry T. Takahashi, Rajiv K. Kalia, Richard W. Roberts   +7 more
wiley   +1 more source

From Panels to Pathogen Networks: The Expanding Role of Targeted Sequencing in Veterinary Medicine. [PDF]

Biology (Basel)
Luo J, Lu W, Liu R, Zhang S, Cao J, Ma C.   +5 more
europepmc   +1 more source

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

ChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source

Droplet-based single-cell RNA sequencing: decoding cellular heterogeneity for breakthroughs in cancer, reproduction, and beyond. [PDF]

J Transl Med
Luo H, Hussain A, Abbas M, Yuan L, Shen Y, Zhang Z, Sun G, Yin X, Huang S.   +8 more
europepmc   +1 more source