Results 181 to 190 of about 213,884 (275)

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

ChemBioChem, Accepted Article.
Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira, Akinobu Nakamura, Kenta Terai, Shinya Tsukiji   +3 more
wiley   +1 more source

Emerging technologies of single-cell multi-omics. [PDF]

Haematologica
Kim YJ, Takahashi K.
europepmc   +1 more source

Morphological Profiling of Imaging Flow Cytometry Data Uncovers Heterogeneity in Infected Gephyrocapsa huxleyi Cultures

Cytometry Part A, EarlyView.
ABSTRACT Phytoplankton, such as the coccolitophore Gephyrocapsa huxleyi (G. huxleyi), has a major ecological impact through photosynthesis—the production of oxygen and organic material. A significant threat to G. huxleyi populations is viral infection with the specific Gephyrocapsa huxleyi virus (GhV).
Maxim Lippeveld, Daniel Peralta, Assaf Vardi, Flora Vincent, Yvan Saeys   +4 more
wiley   +1 more source

Development of a cost-effective high-throughput mid-density 5K genotyping assay for germplasm characterization and breeding in groundnut. [PDF]

Plant Genome
Pandey MK, Sharma V, Khan AW, Joshi P, Gangurde SS, Bajaj P, Janila P, Chitikineni A, Bhat R, Motagi BN, Sangh C, Radhakrishnan T, Bera SK, Gorjanc G, Gujjula KR, Hall N, Carrasco CD, Arjun K, Chandram S, Varshney RK.   +19 more
europepmc   +1 more source

Utilization of high throughput genome sequencing technology for large scale single nucleotide polymorphism discovery in red deer and Canadian elk

, 2016
Rüdiger Bräuning, P. J. Fisher, Alan McCulloch, Russell J Smithies, James F Ward, Matthew J. Bixley, Cindy Lawley, Suzanne J. Rowe, John C. McEwan   +8 more
openalex   +2 more sources

Advanced Imaging and Cytometric Techniques to Characterize Lipid Accumulation in Wolman Disease

Cytometry Part A, EarlyView.
ABSTRACT Wolman disease (WD) is a severe lysosomal storage disorder characterized by fatal lipid accumulation caused by the deficiency of a lipid metabolic enzyme, Lysosomal Acid Lipase (LAL), involved in the lysosomal hydrolysis of cholesterols and triglycerides.
Marine Laurent, Jérémie Cosette, Giulia Pavani, Sarah Bayol, Christine Jenny, Rim Harb, Julie Oustelandt, Anais Brassier, Daniel Stockholm, Mario Amendola   +9 more
wiley   +1 more source

The Need for a Concert of Cytogenomic Methods in Chromosomic Research and Diagnostics. [PDF]

Genes (Basel)
Wang Y, Liehr T.
europepmc   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Seasonal Variations of Community Structure and Functional Genes of <i>Synechococcus</i> in the Subtropical Coastal Waters: Insights from FACS and High-Throughput Sequencing. [PDF]

Microorganisms
Song Z, Zhang T, Liang Y, Mcminn A, Wang M, Jiao N, Luo T.   +6 more
europepmc   +1 more source

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source