Results 251 to 260 of about 15,621,385 (284)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Unlocking the Regulatory Genome: Interpreting the Clinical Impact of Noncoding Variants in Genetic Cardiomyopathies. [PDF]

Circ Genom Precis Med
Renberg A, Coppersmith S, Helms A.
europepmc   +1 more source

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

Food Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu, Jing Liu, Dantong Liu, Menglei Xia, Jia Song, Yu Zheng, Min Wang   +6 more
wiley   +1 more source

Bacterial Lysis Observation Over Time Assay (BLOTS) for High-Throughput Isolation, Sequencing, and Characterization of Bacteriophages. [PDF]

Curr Protoc
Pang SJL, Wee SK, Lee BGW, Yap O, Yap EPH.   +4 more
europepmc   +1 more source

Prevalence, Species Diversity, and Molecular Characterization of Viruses Infecting Phlox (<i>Phlox paniculata</i>) from Botanical Gardens in Russia. [PDF]

Plants (Basel)
Motsar E, Sheveleva A, Sharko F, Tsygankova S, Mitrofanova I, Chirkov S.   +5 more
europepmc   +1 more source

Plant Viral Metagenomic Analysis from a Preliminary Field Survey in Angola Reveals Complex Mixed Infections in Vegetable Crops. [PDF]

Viruses
Amoia SS, Giampetruzzi A, Neto FFS, António LF, Pais da Cunha AT, Minafra A.   +5 more
europepmc   +1 more source

Identification of the Novel HLA-DQB1*02:02:41 Allele by Next-Generation Sequencing. [PDF]

HLA
Harfouch E, Paré B, Chamillard X, Le Toriellec É, Croisille L.   +4 more
europepmc   +1 more source

The Novel HLA-A*02:1229 Allele Was Identified by Next-Generation Sequencing. [PDF]

HLA
Li Y, Chen C, Wang F, Zhang W, Zhu F.
europepmc   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head, Jessica D. Ewald, Niladri Basu   +2 more
wiley   +1 more source

Targeted High-Throughput Sequencing Enables the Detection of Single Nucleotide Variations in CRISPR/Cas9 Gene-Edited Organisms [PDF]

Foods, 2023
Similar to genetically modified organisms (GMOs) produced by classical genetic engineering, gene-edited (GE) organisms and their derived food/feed products commercialized on the European Union market fall within the scope of European Union Directive 2001/18/EC.
Jolien D'Aes, Nancy H C Roosens, Marie-Alice Fraiture   +2 more
exaly   +6 more sources