Results 81 to 90 of about 213,884 (275)

Multiplex restriction amplicon sequencing: a novel next‐generation sequencing‐based marker platform for high‐throughput genotyping

open access: yesPlant Biotechnology Journal, 2019
Summary To enable rapid selection of traits in marker‐assisted breeding, markers must be technically simple, low‐cost, high‐throughput and randomly distributed in a genome.
A. Bernardo   +4 more
semanticscholar   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Genotyping by PCR and High-Throughput Sequencing of Commercial Probiotic Products Reveals Composition Biases.

open access: yesFrontiers in Microbiology, 2016
Recent advances in microbiome research have brought renewed focus on beneficial bacteria, many of which are available in food and dietary supplements. Although probiotics have historically been defined as microorganisms that convey health benefits when ...
Wesley Morovic   +4 more
doaj   +1 more source

BARCOSEL: a tool for selecting an optimal barcode set for high-throughput sequencing

open access: yesBMC Bioinformatics, 2018
Current high-throughput sequencing platforms provide capacity to sequence multiple samples in parallel. Different samples are labeled by attaching a short sample specific nucleotide sequence, barcode, to each DNA molecule prior pooling them into a mix ...
P. Somervuo   +5 more
semanticscholar   +1 more source

Additional file 1 of Correcting nucleotide-specific biases in high-throughput sequencing data

open access: yes, 2017
Figure S1. GM12878 DNase-seq 5-mer tile covariance matrix. The pairwise correlation is shown between bias values of 5-mer tiles in a 160bp window surrounding the 5â end of aligned reads. The block structure between tiles 0 and 3 indicates correlation between adjacent k-mer frequencies within DNase-seq reads. (PDF 203 kb)
Wang, Jeremy   +2 more
openaire   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng   +19 more
wiley   +1 more source

High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing

open access: yesScientific Reports, 2019
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples.
C. Belair   +5 more
semanticscholar   +1 more source

Power and sample size calculations for high-throughput sequencing-based experiments

open access: yesBriefings Bioinform., 2018
Power/sample size (power) analysis estimates the likelihood of successfully finding the statistical significance in a data set. There has been a growing recognition of the importance of power analysis in the proper design of experiments.
Chung-I Li   +4 more
semanticscholar   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

Clinical role of genetic testing for the Brugada syndrome overlapping with arrhythmogenic cardiomyopathy

open access: yesInternational Journal of Arrhythmia
Background Brugada syndrome (BrS) and arrhythmogenic cardiomyopathy (ACM) are inherited cardiac diseases that may predispose to ventricular arrhythmia. Although overlapping features between BrS and ACM have been demonstrated previously, it remains to be ...
Joo Hee Jeong   +9 more
doaj   +1 more source

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