Results 71 to 80 of about 15,584,188 (261)
High-throughput sequencing outputs for each of the depth soundings per transect.
, 2023 High-throughput sequencing outputs for each of the depth soundings per transect.
Ashrenee Govender (6260873) +3 more
core +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
High‐throughput generic single‐entity sequencing using droplet microfluidics
iMetaSingle‐cell sequencing has revolutionized our understanding of cellular heterogeneity by providing a micro‐level perspective in the past decade. While heterogeneity is fundamental to diverse biological communities, existing platforms are primarily ...
Guoping Wang +14 more
doaj +1 more source
Genome reassembly with high-throughput sequencing data
BMC Genomics, 2013 Motivation Recent studies in genomics have highlighted the significance of structural variation in determining individual variation. Current methods for identifying structural variation, however, are predominantly focused on either assembling whole ...
Parrish Nathaniel +2 more
doaj +1 more source
KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes [PDF]
, 2014 High-throughput DNA sequencing produces vast amounts of data, with millions of short reads that usually have to be mapped to a reference genome or newly assembled.
Steiner, Andreas +9 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
New high throughput technologies for DNA sequencing and genomics /
, 2007 Since the independent invention of DNA sequencing by Sanger and by Gilbert 30 years ago, it has grown from a small scale technique capable of reading several kilobase-pair of sequence per day into today's multibillion dollar industry.
Mitchelson, Keith R.
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
SNP discovery by high-throughput sequencing in soybean
BMC Genomics, 2010 Background With the advance of new massively parallel genotyping technologies, quantitative trait loci (QTL) fine mapping and map-based cloning become more achievable in identifying genes for important and complex traits.
Wu Xiaolei +5 more
doaj +1 more source
Virtual Environment for Next Generation Sequencing Analysis [PDF]
, 2012 Next Generation Sequencing technology, on the one hand, allows a more accurate analysis, and, on the other hand, increases the amount of data to process.
Provenzano, R. +6 more
core