Results 11 to 20 of about 118,745 (262)

Effect of GBT440 on oxygen-carrying characteristics and its anti-hypoxia effect in hypoxia animal model

open access: yesDi-san junyi daxue xuebao, 2020
Objective To study the effect of hemoglobin allosteric agent Voxelotor(GBT440) on oxygen-carrying characteristics of blood and its anti-hypoxia effect.
WEI Ming   +4 more
doaj   +1 more source

Evaluation of physico-chemical and heavy metals status in irrigation, stagnant, and Indus River water at the trans-Himalayan region

open access: yesDiscover Water, 2023
The water quality of various resources is changing everywhere, including the high-altitude region, which may have adverse health effects on animals and the human population.
Guru Charan   +3 more
doaj   +1 more source

Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma

open access: yesFrontiers in Oncology, 2019
Hypoxia is a predominant feature in glioblastoma (GBM) and contributes greatly to its drug resistance. However, the molecular mechanisms which are responsible for the development of the resistant phenotype of GBM under hypoxic conditions remain unclear ...
Yixing Gao   +21 more
doaj   +1 more source

High altitude dermatology

open access: yesIndian Journal of Dermatology, 2017
Approximately, 140 million people worldwide live permanently at high altitudes (HAs) and approximately another 40 million people travel to HA area (HAA) every year for reasons of occupation, sports or recreation. In India, whole of Ladakh region, part of Northwest Kashmir, Northern part of Sikkim and Tenga valley of Arunachal are considered inhabited ...
openaire   +3 more sources

Working at High Altitude [PDF]

open access: yesAAOHN Journal, 2011
High altitude is not just an issue for mountain climbers. Elevation can have implications for employees ranging from laborers to office workers to scientists. Awareness is key to effective management.
openaire   +2 more sources

IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression

open access: yesFrontiers in Physiology, 2021
Background: Neuron apoptosis, regulated by endoplasmic reticulum (ER) stress in the hippocampus, is an essential factor influencing the cognitive impairment induced by hypobaric hypoxia.
Simin Zhou   +26 more
doaj   +1 more source

Hematological Risk Factors for High-Altitude Headache in Chinese Men Following Acute Exposure at 3,700 m

open access: yesFrontiers in Physiology, 2017
Background: High-altitude headache (HAH) is a notably common disorder affecting the daily life of travelers ascending to high altitude. Hematological parameters are important clinical examinations for various diseases.
He Huang   +18 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Adropin Is a Key Mediator of Hypoxia Induced Anti-Dipsogenic Effects via TRPV4-CamKK-AMPK Signaling in the Circumventricular Organs of Rats

open access: yesFrontiers in Molecular Neuroscience, 2017
Water intake reduction (anti-dipsogenic effects) under hypoxia has been well established, but the underlying reason remains unknown. Our previous report indicated that activated TRPV4 neurons in SFO are associated with anti-dipsogenic effects under ...
Qing-Yuan Huang   +19 more
doaj   +1 more source

Identification of a miRNA–mRNA Regulatory Networks in Placental Tissue Associated With Tibetan High Altitude Adaptation

open access: yesFrontiers in Genetics, 2021
The Tibetan population has lived and successfully reproduced at high altitude for many generations. Studies have shown that Tibetans have various mechanisms for protection against high-altitude hypoxia, which are probably due, at least in part, to ...
Noryung Tenzing   +22 more
doaj   +1 more source

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