Results 101 to 110 of about 3,603,990 (303)

Association between patients with dementia and high caregiving burden for caregivers from a medical center in Taiwan

open access: yesPsychology Research and Behavior Management, 2019
Guei-Jhen Yan,1 Wen-Fu Wang,2,3 Kai-Ming Jhang,4 Che-Wei Lin,5 Hsin-Hung Wu6,7 1Secretary Office, Chuanghua Christian Hospital, Changhua, Taiwan; 2Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan; 3Department of Holistic Wellness ...
Yan GJ, Wang WF, Jhang KM, Lin CW, Wu HH
doaj  

Injury burden due to high temperature based on global burden of disease data from 1990 to 2021

open access: yesDiscover Public Health
Background Extreme heat is an emerging injury risk. We aimed to quantify the global burden of injuries attributable to high temperature from 1990 to 2021 using age-standardized mortality rates (ASMR) and age-standardized disability-adjusted life-year ...
Zeeshan Ahsan, Mehak Ahsan
doaj   +1 more source

Ukraine set to act on high suicide burden [PDF]

open access: yesInjury Prevention, 2007
Having survived multiple catastrophes in the 20th century, newly independent Ukraine now has some of the highest injury death rates in Europe. The nation’s most common type of injury death is suicide, and its rate is one of Europe’s and the world’s highest. Alcohol abuse occurs in 20% of men, and major depression in 20% of women. Suicide is the leading
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Labour Tax Reform, The Good Jobs and the Bad Jobs. [PDF]

open access: yes
We analyse recent proposals to shift the tax burden away from low-paid labour, assuming a dual labour market where the 'good' high-paying jobs are rationed. A shift in the tax burden from low-paid to high-paid workers has an ambiguous effect on the level
Henrik Jacobsen Kleven   +1 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Treatment outcomes in NTM-PD in a high TB burden context

open access: yesIJTLD Open
BACKGROUND: Non-tuberculous mycobacterial (NTM) pulmonary disease (PD) is a significant concern in China, compounding the existing burden of TB. This review aims to summarise the treatment outcomes for NTM-PD in China.
S. Kang   +3 more
doaj   +1 more source

Characteristics Predicting a High Caregiver Burden in Patients with Vascular Cognitive Impairment: Using the Apriori Algorithm to Delineate the Caring Scenario

open access: yesRisk Management and Healthcare Policy, 2021
Kai-Ming Jhang,1,* Wen-Fu Wang,1,2,* Hsin-Fang Chang,3,* Ming-Che Chang,4 Hsin-Hung Wu3,5,6 1Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan; 2Department of Holistic Wellness, Ming Dao University, Changhua, Taiwan; 3Department of ...
Jhang KM   +4 more
doaj  

High Burden of Staphylococcal Disease in Indigenous Communities [PDF]

open access: yesThe Journal of Infectious Diseases, 2009
Numerous studies in the past 2 decades have recorded an apparently high rate of Staphylococcus aureus infection in socalled indigenous populations in particular, a high rate of infection caused by methicillin-resistant strains of S. aureus (MRSA) [1], Such problems have been documented among Native Americans [2], Pacific Islanders in Hawaii [3 ...
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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