Results 261 to 270 of about 1,420,424 (313)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Emerging In Vivo Imaging Modalities for Improved Glioblastoma Surgery and Monitoring. [PDF]

Biomedicines
Dada O, Singh S, Sumadchat F, Lather M, Brooks B, Allgood JE.   +5 more
europepmc   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Sensing Technologies and Physiological Parameters for Real-Time Driver Drowsiness Detection: A Comprehensive Review. [PDF]

Sensors (Basel)
El Sahmarany L, Alkhaldi M, Alzahrani SI.   +2 more
europepmc   +1 more source

Real-time medical images enhancement technique using Adaptive Histogram Equalization model. [PDF]

Sci Rep
Dhaka A, Sharma AK, Nandal A.
europepmc   +1 more source

Comparative validation of intraoperative ultrasound versus intraoperative cholangiography for the detection of choledocholithiasis. [PDF]

Langenbecks Arch Surg
Tresierra L, Facundo HCG, Arevalo CAL, Llorente AS, Ortega JCC, Martínez SG.   +5 more
europepmc   +1 more source

Potential Benefits of Ultra-High Field MRI for Embryonic and Fetal Brain Investigation: A Comprehensive Review. [PDF]

Diagnostics (Basel)
Boitor D, Oancea M, Farcasanu A, Simon S, Muresan D, Rotar IC, Nemeti GI, Goidescu I, Staicu A, Surcel M.   +9 more
europepmc   +1 more source

Optimizing imaging in orbital vascular anomalies: a review on matching modality to pathology for effective diagnosis and treatment planning. [PDF]

Front Ophthalmol (Lausanne)
Arjomandi A, Lucarelli KM, Goldberg RA, Rootman DB.   +3 more
europepmc   +1 more source

Deep learning reconstruction improves detection of focal liver lesions in hepatobiliary phase compared to conventional EOB-MRI. [PDF]

Front Med (Lausanne)
Peng X, Cheng Q, Tian R, Lang L, Li C, Tao R, Xu T, Pylypenko D, Zuo L, Yu D, Lv W.   +10 more
europepmc   +1 more source

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Nonlinear technique for the enhancement of extremely high contrast images

SPIE Proceedings, 2008
An adaptive technique for image enhancement based on a specifically designed nonlinear function is presented in this paper. The enhancement technique constitutes three main processes-adaptive intensity enhancement, contrast adjustment, and color restoration.
Numan Unaldi, Saibabu Arigela, Vijayan K. Asari, Zia-ur Rahman 0001   +3 more
openaire   +1 more source