Results 51 to 60 of about 531,330 (353)

Relationship Between Physical Conditioning and Plasma High Density Lipoprotein-Cholesterol Concentration [PDF]

, 1983
Five subjects (three females and two males) took part in an exercise regimen in order to determine if aerobic exercise results in an increase in high-density lipoprotein-cholesterol levels (HDL-C) in the plasma.
Baeyens, Dennis A., Morgans, Leland F., Morris, Manford D.   +2 more
core   +2 more sources

Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study [PDF]

, 2015
Objectives The interleukin-6 receptor (IL-6R) blocker tocilizumab (TCZ) reduces inflammatory disease activity in rheumatoid arthritis (RA) but elevates lipid concentrations in some patients.
Bathon, Joan M., Beaulieu, Andre D., Carlson, Timothy H., Codding, Christine E., Delles, Christian, Giles, Jon T., Lee, Janet S., McInnes, Iain B., Salmon, Jane E., Sattar, Naveed, Thompson, Liz   +10 more
core   +1 more source

High-Density Lipoproteins [PDF]

Journal of the American College of Cardiology, 2012
The substantial residual cardiovascular events present in statin-treated patients provide a challenge to researchers in the cardiovascular field to develop additional therapeutic approaches. In cardiovascular disease (CVD) epidemiology, few associations are as consistent and enduring as the ...
Chunyu Zheng, Masanori Aikawa
openaire   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

SR-BI-mediated selective lipid uptake segregates apoA-I and apoA-II catabolism

Journal of Lipid Research, 2005
The HDL receptor scavenger receptor class B type I (SR-BI) binds HDL and mediates the selective uptake of cholesteryl ester. We previously showed that remnants, produced when human HDL2 is catabolized in mice overexpressing SR-BI, become incrementally ...
Maria C. de Beer, Deneys van der Westhuyzen, Nathan L. Whitaker, Nancy R. Webb, Frederick C. de Beer   +4 more
doaj  

Role of Gamma Glutamyl Transferase in the Diagnosis of Metabolic Syndrome in Patients with Hypothyroidism [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Hypothyroidism is the most prevalent thyroid disorder in India that affects one in ten adults. Gamma Glutamyl Transferase (GGT) is an ectopic enzyme associated with oxidative stress in various diseased conditions.
ME Sumathi, K Prabhavathi, S Harish Kumar, KN Shashidhar, V Mahesh   +4 more
doaj   +1 more source

Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. [PDF]

, 2016
BackgroundGlycosylation patterns of serum proteins, such as α1-acid glycoprotein, are modified during an acute phase reaction. The response of acute Kawasaki disease (KD) patients to IVIG treatment has been linked to sialic acid levels on native IgG ...
Burns, Jane C, Connelly, Margery A, Kanegaye, John T, Otvos, James D, Pourfarzib, Ray, Shalaurova, Irina, Shimizu, Chisato, Tremoulet, Adriana H, Winegar, Deborah A   +8 more
core   +3 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

Journal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger, Markus Heine, Roshni Singaraja, Michael Hayden, May Brundert, Rajasekhar Ramakrishnan, Joerg Heeren   +6 more
doaj  

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A., Caslake, M.J., Cooney, J., Freeman, D.J., Griffin, B.A., Meyer, B.J., Nilsson, S., Olivecrona, G., Ramsay, J.E., Stewart, F.M.   +9 more
core   +2 more sources