Results 61 to 70 of about 2,028,498 (355)

Management of triglycerides, non-high density lipoprotein cholesterol and high density lipoprotein cholesterol

Indian Heart Journal
Dyslipidaemia characterised by elevated total cholesterol/LDL-C, triglyceride or both or decreased HDL-C is an important risk factor for the development of ASCVD. Atherogenic dyslipidaemia characterised by high TG, low HDL-C and elevated small dense LDL (
Geevar Zachariah
doaj   +1 more source

High density lipoprotein mimicking nanoparticles for atherosclerosis

Nano Convergence, 2020
Atherosclerosis is a major contributor to many cardiovascular events, including myocardial infarction, ischemic stroke, and peripheral arterial disease, making it the leading cause of death worldwide.
Jun Chen, Xixi Zhang, Reid Millican, Jacob Emil Creutzmann, Sean Martin, Ho-Wook Jun   +5 more
doaj   +1 more source

Lipoprotein subfraction patterns throughout gestation in The Gambia: changes in subfraction composition and their relationships with infant birth weights

Lipids in Health and Disease, 2023
Background Lipoprotein subfraction concentrations have been shown to change as gestation progresses in resource-rich settings. The objective of the current study was to evaluate the impact of pregnancy on different-sized lipoprotein particle ...
Jessica G. Woo, John T. Melchior, Debi K. Swertfeger, Alan T. Remaley, Ebrima A. Sise, Fatou Sosseh, Jeffrey A. Welge, Andrew M. Prentice, W. Sean Davidson, Sophie E. Moore, Laura A. Woollett   +10 more
doaj   +1 more source

High-Density Lipoproteins in Stroke [PDF]

, 2014
Besides their well-documented function of reverse transport of cholesterol, high-density lipoproteins (HDLs) display pleiotropic effects due to their antioxidant, antithrombotic, anti-inflammatory and antiapoptotic properties that may play a major protective role in acute stroke, in particular by limiting the deleterious effects of ischaemia on the ...
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Association between Non high density lipoprotein to high density lipoprotein cholesterol ratio and bone mineral density

Scientific Reports
NHHR is the new composite lipid index. There are few studies on the relationship between NHHR and bone mineral density (BMD). This study aimed to investigate the correlation between the NHHR and BMD. Weighted multiple linear regression, threshold effects,
Ying Zhou, Ning Su, Huimin Dai, Guowei Ma, Rui Yin, Jiajia Sheng, Mingxia Quan, Liu Yang, Jie Chen   +8 more
doaj   +1 more source

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

European Heart Journal, 2011
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically appraise evidence for elevated levels of triglyceride-rich lipoproteins (
M. Chapman, H. Ginsberg, P. Amarenco, F. Andreotti, J. Borén, A. Catapano, O. Descamps, E. Fisher, P. Kovanen, J. Kuivenhoven, P. Lesnik, L. Masana, B. Nordestgaard, Kausik K. Ray, Ž. Reiner, M. Taskinen, L. Tokgözoğlu, A. Tybjærg-Hansen, Gerald F. Watts   +18 more
semanticscholar   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

The High Density Lipoprotein Cholesterol Hypothesis Revisited

Indonesian Biomedical Journal, 2018
BACKGROUND: The strong inverse association of plasma levels of high-density lipoprotein cholesterol (HDL-C) with coronary heart disease (CHD) found in human epidemiological studies led to the development of the ‘HDL-C hypothesis’, which posits that ...
Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya   +2 more
doaj   +1 more source