Results 51 to 60 of about 69,901 (166)

High-Density Lipoprotein [PDF]

Circulation Research, 2013
Despite numerous epidemiological studies demonstrating that high-density lipoprotein cholesterol (HDL-C) levels are inversely associated with cardiovascular risk,1–3 several lines of evidence now indicate that targeting HDL-C levels to reduce the risk of cardiovascular events is unlikely to be effective.
Ali, Javaheri, Daniel J, Rader
openaire   +2 more sources

Atherogenic Index of Plasma an Indicator for Predicting Cardiovascular Risk in Addition to Endothelial Dysfunction in Type 2 Diabetic Subjects [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Prevalence of Cardiovascular Disease (CVD) in diabetic subjects is higher than that in the general population. Dyslipidaemia is a known atherogenic factor which causes vascular complications in both general and diabetic population ...
Siva Prasad Palem, Philips Abraham
doaj   +1 more source

Role of Gamma Glutamyl Transferase in the Diagnosis of Metabolic Syndrome in Patients with Hypothyroidism [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Hypothyroidism is the most prevalent thyroid disorder in India that affects one in ten adults. Gamma Glutamyl Transferase (GGT) is an ectopic enzyme associated with oxidative stress in various diseased conditions.
ME Sumathi, K Prabhavathi, S Harish Kumar, KN Shashidhar, V Mahesh   +4 more
doaj   +1 more source

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and osteoporotic fracture

Frontiers in Medicine
BackgroundThe non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio (NHHR) has emerged as a valuable lipid marker associated with various cardiometabolic diseases. Although evidence links lipid metabolism to skeletal health,
Jie Deng, Jie Deng, Mengmeng Shang, Mengmeng Shang, Junhao Jin, Junhao Jin, Suhong Wei, Suhong Wei   +7 more
doaj   +1 more source

1H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures

Journal of Lipid Research, 2019
NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark, Werner Kremer, Alfred Boettcher, Christina Schreier, Paul Sander, Gerd Schmitz, Renate Kirchhoefer, Fritz Huber, Hans Robert Kalbitzer   +8 more
doaj   +1 more source

HDL-apolipoprotein A-I exchange is independently associated with cholesterol efflux capacity

Journal of Lipid Research, 2015
HDL is the primary mediator of cholesterol mobilization from the periphery to the liver via reverse cholesterol transport (RCT). A critical first step in this process is the uptake of cholesterol from lipid-loaded macrophages by HDL, a function of HDL ...
Mark S. Borja, Kit F. Ng, Angela Irwin, Jaekyoung Hong, Xing Wu, Daniel Isquith, Xue-Qiao Zhao, Bryan Prazen, Virginia Gildengorin, Michael N. Oda, Tomáš Vaisar   +10 more
doaj   +1 more source

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans

Journal of Lipid Research, 2017
Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis.
Marina Cuchel, Anna C. Raper, Donna M. Conlon, Daniel A. Pryma, Richard H. Freifelder, Rahul Poria, Debra Cromley, Xiaoyu Li, Richard L. Dunbar, Benjamin French, Liming Qu, William Farver, Ching-Chiang Su, Sissel Lund-Katz, Amanda Baer, Giacomo Ruotolo, Peter Akerblad, Carol S. Ryan, Lan Xiao, Todd G. Kirchgessner, John S. Millar, Jeffrey T. Billheimer, Daniel J. Rader   +22 more
doaj   +1 more source

High-density lipoprotein impedes glycation of low-density lipoprotein

Diabetes and Vascular Disease Research, 2012
Glycation of low-density lipoprotein (LDL) increases its atherogenicity, but whether high-density lipoprotein (HDL) can protect LDL against glycation is not known. LDL and HDL were isolated from 32 volunteers with serum HDL cholesterol concentrations ranging from 0.76 to 2.01 (mean = 1.36) mmol/L.
Nahla N, Younis, Handrean, Soran, Valentine, Charlton-Menys, Reena, Sharma, Salam, Hama, Philip, Pemberton, Mohamed M, Elseweidy, Paul N, Durrington   +7 more
openaire   +2 more sources

Effect of Poloxamer 407 on serum VLDL, LDL and HDL levels of rabbits

National Journal of Physiology, Pharmacy and Pharmacology, 2014
Background: Poloxamer 407 is used in parenteral formulations as solubilizing and wetting agent for traditional, low-molecular-weight organic drug molecules and as stabilizing agent for proteins and polypeptide drugs.
Harish Govind Naik, Ashwini Kolur, Dundesh Maled, Chitra C Khanwelkar, Rohit Desai, Sunil Gidamudi   +5 more
doaj   +1 more source

Hepatic lipase activity is lower in African American men than in white American men: effects of 5′ flanking polymorphism in the hepatic lipase gene (LIPC)

Journal of Lipid Research, 1998
Plasma high density lipoprotein cholesterol (HDL-C) concentrations are higher in African American men than in white men, but the mechanism(s) responsible for this ethnic difference has not been elucidated.
Gloria Lena Vega, Luther T. Clark, Aylmer Tang, Santica Marcovina, Scott M. Grundy, Jonathan C. Cohen   +5 more
doaj   +1 more source