Results 51 to 60 of about 2,028,498 (355)

Inverse Association Between Serum Non–High‐Density Lipoprotein Cholesterol Levels and Mortality in Patients Undergoing Incident Hemodialysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background There is accumulating evidence that serum levels of non–high‐density lipoprotein cholesterol (non–HDL‐C) are a more accurate predictor of cardiovascular outcomes when compared with low‐density lipoprotein cholesterol.
Tae Ik Chang, Elani Streja, Gang Jee Ko, Neda Naderi, Connie M. Rhee, Csaba P. Kovesdy, Moti L. Kashyap, Nosratola D. Vaziri, Kamyar Kalantar‐Zadeh, Hamid Moradi   +9 more
doaj   +1 more source

Maturation of high-density lipoproteins

Journal of The Royal Society Interface, 2009
Human high-density lipoproteins (HDLs) are involved in the transport of cholesterol. The mechanism by which HDL assembles and functions is not well understood owing to a lack of structural information on circulating spherical HDL. Here, we report a series of molecular dynamics simulations that describe the maturation of discoidal HDL into spherical HDL
Amy Y, Shih, Stephen G, Sligar, Klaus, Schulten   +2 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Light and electron microscopical observations of the effects of high-density lipoprotein on growth of Plasmodium falciparum in vitro [PDF]

, 2004
Author Posting. © Cambridge University Press, 2004. This article is posted here by permission of Cambridge University Press for personal use, not for redistribution.
Ferguson, D. J. P., Schiflett, A, Ferguson, DJP, Hajduk, Stephen L., Ferguson, DJ, Drain, J, Day, K. P., Drain, J., Carter, M., Imrie, H, Hajduk, SL, Schiflett, A., Carter, M, Imrie, H., Day, KP   +14 more
core   +1 more source

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Nature Genetics, 2008
Blood concentrations of lipoproteins and lipids are heritable risk factors for cardiovascular disease. Using genome-wide association data from three studies (n = 8,816 that included 2,758 individuals from the Diabetes Genetics Initiative specific to the ...
S. Kathiresan, S. Kathiresan, O. Melander, C. Guiducci, Aarti Surti, N. Burtt, M. Rieder, G. Cooper, C. Roos, B. Voight, B. Voight, A. Havulinna, B. Wahlstrand, T. Hedner, D. Corella, E. Tai, J. Ordovás, G. Berglund, E. Vartiainen, P. Jousilahti, B. Hedblad, M. Taskinen, C. Newton‐Cheh, C. Newton‐Cheh, V. Salomaa, L. Peltonen, L. Groop, L. Groop, D. Altshuler, M. Orho-Melander   +29 more
semanticscholar   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Association of Hypertensive Retinopathy with different serum lipid parameters in patients of Essential Hypertension: A Hospital Based Study

Journal of Nobel Medical College, 2018
Introduction: Abnormalities in serum lipid and lipoprotein levels are recognized as major modifiable risk factors for cardiovascular disease and essential hypertension and retinopathy.
Bishwa Nath Adhikari, Pramod Sharma Gautam, Binod Bekoju, Sadhana Basnet, Himlal Bhandari   +4 more
doaj   +1 more source

High-Density Lipoproteins and Serum Amyloid A (SAA)

Current Atherosclerosis Reports, 2021
Serum amyloid A (SAA) is a highly sensitive acute phase reactant that has been linked to a number of chronic inflammatory diseases. During a systemic inflammatory response, liver-derived SAA is primarily found on high-density lipoprotein (HDL).
N. Webb
semanticscholar   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Arginine-directed glycation and decreased HDL plasma concentration and functionality [PDF]

, 2014
Background/Objectives: Decreased plasma concentration of high-density lipoprotein cholesterol (HDL-C) is a risk factor linked to increased risk of cardiovascular disease (CVD). Decreased anti-atherogenic properties of HDL are also implicated in increased
Rabbani, Naila, Smith, L., Godfrey, L. (Lisa), Thornalley, Paul J., Yamada-Fowler, N. (Naomi)   +4 more
core   +1 more source