Results 241 to 250 of about 21,716,016 (301)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Role of High-Dose-Rate Brachytherapy (Interventional Radiotherapy) in the Reirradiation of Liver Metastases. [PDF]

Cancers (Basel)
Cisek P, Kordzińska-Cisek I, Kozłowska A, Grzybowska-Szatkowska L.   +3 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Magnetic resonance imaging-guided salvage high-dose-rate brachytherapy for local recurrence after prostatectomy and external beam radiotherapy. [PDF]

J Contemp Brachytherapy
Willisch P, Vázquez-Barreiro B, Candal A, Vilchez A, Andrade B, Lopez-Soliño S, Cespón E, Montemuiño S, Nieto I, Carballo-Quinta M, de la Torre MV, Gomez FS, López AM, Muñoz V.   +13 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Impact of catheter positioning on planned target volume (PTV) coverage and organs at risk (OARs) in high-dose-rate (HDR) endotracheal brachytherapy: a comparative 2D vs 3D study. [PDF]

Int J Med Sci
Castellón JN, Cacho IF, Carrizosa ML, Villoslada CI, Morcillo MD, Esteban EC, Bueno PS, Zarrabeitia ZZ, Sanz AP, Pérez NC, Avedillo FSM, Gallego MC, Ortega MA, García MS.   +13 more
europepmc   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

New modalities for ultra-high dose rate irradiation and FLASH experiments. [PDF]

Phys Imaging Radiat Oncol
Adrian G, Moeckli R, Beyreuther E, Muren LP, Sørensen BS.   +4 more
europepmc   +1 more source

Concurrent chemoradiation and high-dose-rate brachytherapy for synchronous muscle-invasive bladder carcinoma and very high-risk prostate adenocarcinoma: A case report. [PDF]

J Contemp Brachytherapy
Watts S, Hanus E, Awan S, Badkul R, Caracioni AA, Shiao JC.   +5 more
europepmc   +1 more source

Polish Brachytherapy Society clinical recommendations and expert consensus on radical high-dose-rate brachytherapy for prostate cancer. [PDF]

J Contemp Brachytherapy
Chyrek AJ, Hetnał M, Kukiełka A, Lelek P, Kluska A, Romaniszyn A, Samołyk-Kogaczewska N, Burchardt W, Cisek P, Krzysztofiak T, Kolbusz M, Kazalski D, Filipowski T, Kazberuk D, Szmigiel-Trzcin'ska A, Celarek K, Madej P, Konat-Ba Ska K, Lichon' K, Matys R, Bilski M, Burchardt E, Stankiewicz M, Chicheł A, Wojcieszek P.   +24 more
europepmc   +1 more source