Results 71 to 80 of about 1,974,678 (268)
High-Efficiency High-NA Metalens Designed by Maximizing the Efficiency Limit
We identify optimal system parameters that maximize the upper limit of transmission efficiency and then perform inverse design to find high-NA wide-field-of-view metalenses with a record-high efficiency (98% transmission, 92% Strehl ratio, NA = 0.9).
Li, Shiyu, Lin, Ho-Chun, Hsu, Chia Wei
openaire +2 more sources
地球温暖化に伴う温室効果ガス(CO2等)排出削減,省エネルギー面でも,環境問題への関心が高まっている。当社では,長年培ってきた技術とノウハウにより,最高レベルの「高効率ファン」開発に成功した。商品開発は,送風機自体の効率改善を優先させ,比較的大型で消費電力量が大きな機種からモデルチェンジを進めている。製紙業界では,送風機専門用語の比速度700が一般的に使用されてきたが,機器の高速化・小型化に伴い,今後は,大風量―高静圧の比速度500クラスの送風機が増加するものと予想される。当社は,次代を先取りし,比速度500と700高効率新型機を相次いで開発・市場投入した。本稿では,送風機高効率化に纏わる開発過程から市場投入までのエピソードを交え,「高効率ファン」の優位性について紹介する。
Hidemitsu Nagai, Yoshimasa Watanabe
openaire +2 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The present study aims to explore the physico-chemical structure evolution characteristic during Yangchangwan bituminous coal (YCW) gasification in the presence of iron-based waste catalyst (IWC). The catalytic gasification reactivity of YCW was measured
Xinsha Zhang +6 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

