Results 71 to 80 of about 73,716 (295)

Dynamic response of polymethacrylimide foam sandwich structures with different core layers under water impact loading

open access: yesDefence Technology
Polymethacrylimide (PMI) foam has the highest specific stiffness and strength among polymer foams, with excellent radar-absorbing capabilities, which provide it with broad prospects in underwater applications.
Peilin Zhu   +4 more
doaj   +1 more source

Analysis of global momentum transfer due to buried mine detonation

open access: yesDefence Technology, 2019
The emergence of improvised explosive devices (IED) significantly extended the spectrum of possible threat mechanisms to military vehicles and their occupants.
N. Heider, V. Denefeld, H. Aurich
doaj   +1 more source

EXPERIMENTAL RESEARCH OF CONTROLLING HIGH VOLTAGE TRANSFORMER WINDING CONDITION BASED ON SWITCHING IMPULSES

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2020
The importance of the research is driven by the exceptional importance of stable work of electrical equipment complex which is used at production, transportation and processing of geo-resources. Effectiveness and reliability of such geological production is strongly depends on high voltage transformer condition.
Valeriy A. Lavrinovich   +2 more
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Optimising low acoustic impedance back-fill material wave barrier dimensions to shield structures from ground borne high speed rail vibrations [PDF]

open access: yes, 2013
Ground borne vibrations generated due to high speed train passage can cause undesirable effects on the nearby environment. One approach to mitigate vibration levels is to use "wave barriers", however their installation cost may be very high.
Giannopoulos, A   +9 more
core   +1 more source

Atmospheric Conditions Correction for Positive Switching Breakdown Voltage of 1-m Rod-Plate Gap

open access: yesIEEE Access
As converter stations are increasingly constructed at high altitudes, how to reasonably select the minimum air spacing of converter station substation equipment has become an important issue for DC power transmission at high altitudes.
Yong Sun   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

High power impulse magnetron sputtering under industrial conditions [Elektronisk resurs] [PDF]

open access: yes, 2011
In this thesis, the recent development step of magnetron sputtering, termed high power impulse magnetron sputtering (HiPIMS) has been studied. Compared to conventional magnetron sputtering HiPIMS provides a higher plasma density which can ionise the ...
Samuelsson, Mattias,   +5 more
core  

Home - About - Disclaimer - Privacy