Results 61 to 70 of about 20,769,142 (287)

EXPERIMENTAL RESEARCH OF CONTROLLING HIGH VOLTAGE TRANSFORMER WINDING CONDITION BASED ON SWITCHING IMPULSES

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2020
The importance of the research is driven by the exceptional importance of stable work of electrical equipment complex which is used at production, transportation and processing of geo-resources. Effectiveness and reliability of such geological production is strongly depends on high voltage transformer condition.
Valeriy A. Lavrinovich   +2 more
openaire   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Impulse Characteristics of Soil Treated with Enhancement Materials and Various Moisture Contents

open access: yesApplied Sciences
Due to the high mineral contents of additives and enhancement materials (EMs), EMs have become popular in treating soil, which expectedly improves the electrical characteristics of soil.
Usman Muhammad   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Reconfiguration strategy of shipboard power system adapting to impulse load access

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveShipboard power systems (SPS) are vulnerable to attacks, often resulting in a degraded or partially damaged state. In this state, the system exhibits low inertia, and the connection of critical loads, mainly high-power impulse loads, may cause ...
Ang XU, Xingbao JU, Fanrong WEI
doaj   +1 more source

To Buy Or Not To Buy? A Behavioural Approach to Examine Consumer Impulse Buying Choice in Various Situations [PDF]

open access: yes, 2013
Impulse buying is a phenomenon that has attracted attention from marketers and consumer researchers for decades. Whilst impulse buying has been studied extensively, there is a gap in our understanding of consumer impulse buying ...
MA, WEI,CHEN
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Dynamic response of polymethacrylimide foam sandwich structures with different core layers under water impact loading

open access: yesDefence Technology
Polymethacrylimide (PMI) foam has the highest specific stiffness and strength among polymer foams, with excellent radar-absorbing capabilities, which provide it with broad prospects in underwater applications.
Peilin Zhu   +4 more
doaj   +1 more source

Influence of Discharge Energy on the Morphology and Optical Response of Tungsten Oxide Thin Films Deposited by Reactive High-Power Impulse Sputtering in a Facing-Target Configuration [PDF]

open access: yesMaterials Research
Tungsten oxide thin films were deposited by reactive high-power impulse sputtering using a facing-target configuration (HiP-FTS), and the influence of discharge energy on film morphology and hydrogen response was investigated.
Yoji Yasuda
doaj   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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