Results 61 to 70 of about 70,024 (254)

Ultrasonic regeneration of activated carbon with the addition of gas flushing

Desalination and Water Treatment
In this study, we investigated the effects of four operating parameters; frequency, power, gas impulse intensity, and regeneration time, on the regeneration of activated carbon.
Zhiwei Wang, Bingjie Zhou, Zhendong Liu, Lu Li, Kemei Zhou, Tian Tian, Binbin Wu, Wanting Feng, Yuanxiang Shan, Hongqin Xue, Zheng Wang   +10 more
doaj   +1 more source

Experimental and numerical investigation of design optimization of a partial admitted supersonic turbine

Propulsion and Power Research, 2013
To obtain a high specific work output, the large pressure ratios across the turbine are required. This can be achieved using a supersonic turbine. When the fluid mass flow is low, the impulse kind of one or two stages supersonic turbine is employed.
Reza Aghaei tog, Abolghasem M. Tousi
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Blast characteristics of center-initiated cylindrical charge in high-altitude environments

AIP Advances
The effects of different high-altitudes on the blast parameters—including peak overpressure and specific impulse—produced by a center-initiated cylindrical charge (CC) were simulated using the AUTODYN software and analyzed through dimensional analysis ...
Rui Li, Rui Sun, Ming-hang Hu, Ya-jing Chen, Quan Wang, Dong-Dong Zhang, Xue-jiao Li, Xiao-rong Cui   +7 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Investigation on the Resonant Oscillations in an 11 kV Distribution Transformer under Standard and Chopped Lightning Impulse Overvoltages with Different Shield Placement Configurations

Energies, 2019
This paper presents an investigation on the resonant oscillations of an 11 kV layer-type winding transformer under standard and chopped lightning impulse overvoltage conditions based on calculated parameters. The resistances, inductances and capacitances
Avinash Srikanta Murthy, Norhafiz Azis, Mohd Fairouz Mohd Yousof, Jasronita Jasni, Mohammad Lutfi Othman, Mohd Aizam Talib, Bhaba Priyo Das   +6 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Acute Effects of Low vs. High Inertia During Flywheel Deadlifts with Equal Force Impulse on Vertical Jump Performance

Sensors
Background: Flywheel resistance training has gained popularity due to its ability to induce eccentric overload and improve strength and power. This study examined the acute effects of low- (0.025 kg·m2) versus high-inertia (0.10 kg·m2) flywheel deadlifts,
Athanasios Tsoukos, Margarita Tsoukala, Dimitra Mirto Papadimitriou, Gerasimos Terzis, Gregory C. Bogdanis   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source