Results 21 to 30 of about 71,827 (219)

Electroacoustic Analysis and Optimization of Needle-Rod Electrodes for Low-Power Impulse Sound Source

Sensors
In acoustic deep detection technology, conventional monopole, dipole, and phased-array sound sources are far inferior to impulsive sound sources in frequency and amplitude.
Xiao Du, Jing Zhou, Xu Gao
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Effect of Enhancement Material on the Performance of Ground Electrodes Under Impulse Conditions

IEEE Access
Among the factors that affect the soil resistivity is the chemical content in soil, where the ionic conduction is expectedly increased and the soil resistivity is reduced.
Usman Muhammad, Nurul Nadia Ahmad, Normiza Mohamad Nor, Fazlul Aman   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

[2+2] and [2+1] cycloaddition of myrcene for synthesis of highly strained bio-fuels with high density and high impulse

Energetic Materials Frontiers
Developing bio-fuels provides a sustainable strategy to reduce the dependence on finite fossil fuels. But biomass-based fuel molecules usually lack strained structure, resulting in undesirable density and impulse for aerospace applications.
Jin-xiu Hu, Min-hua Ai, Xian-long Liu, Xiao-lei Guo, Cheng-xiang Shi, Kang Xue, Xiang-wen Zhang, Li Wang, Ji-Jun Zou, Lun Pan   +9 more
doaj   +1 more source

"Effects of electrohydroimpulse discharges on the crushing of the natural mineral quartz "

Eurasian Physical Technical Journal, 2019
Electro-hydro-impulse (high-current discharge in water) also belongs to the technologies using strong impulse currents. With a powerful pulsed electric discharge between the electrodes placed in the liquid, an electro-hydraulic effect occurs.
G.A. Bulkairova, M. Stoev, A.K. Khassenov, D.Zh. Karabekova, Zh.G. Nurgaliyeva, M.S. Kipshakov   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Impulse Characteristics of Various Soil-Enhancement Material Mixtures

Applied Sciences
Many studies have demonstrated that a reduction in ground impedance value occurs under high-impulse current magnitudes, due to the ionisation process in soil.
Fazlul Aman, Usman Muhammad, Normiza Mohamad Nor, Haziah Abdul Hamid   +3 more
doaj   +1 more source

Potentials' distribution in high resistivity soil around extended grounding electrodes [PDF]

Vestnik MGTU, 2016
The potential distribution in high resistivity soil around extended grounding electrodes has been described in the paper. The high-voltage polygon has been developed for experimental investigation.
Ivonin V. V.
doaj   +1 more source