Results 101 to 110 of about 445,213 (310)
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
PENGGUNAAN HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) DALAM PROSES ANALISA DETEKSI ION
RINGKASAN Proses pemurnian NaCl di LAPAN membutuhkan perlakuan analisa deteksi ion, yang mempunyai tujuan untuk mengetahui seberapa besar konsentrasi ion (khususnya kation) yang terkandung di dalam larutan NaCl sebelum dan sesudah dimurnikan.
Retno Ardianingsih
core
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Claire M. Peppiatt-Wildman +18 more
core +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF AMINO-ACIDS, PEPTIDES AND PROTEINS .74.
MTW HEARN (15805409) +2 more
core
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Separation of structurally similar protoberberine alkaloids from Corydalis yanhusuo W.T.Wang in reversed-phase high-performance liquid chromatography with chaotropic ...
杜娜娜 +4 more
core
Quantitation of Total And Reduced Glutathione In Erythrocytes By High Performance Liquid Chromatography] [PDF]
Glutathione is the main non-protein thiol compound present in mammalian cells inmillimolar level. Glutathione which is a tripeptide functions as a principle reducingagent in biological systems. The most important function of this tripeptide is tomaintain
1,3Zahide Çavdar, +4 more
doaj
Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo +3 more
wiley +1 more source

