Results 41 to 50 of about 1,484,765 (329)

Determination of the Permeation and Penetration of Flurbiprofen into Cadaveric Human Pharynx Tissue

Clinical Pharmacology: Advances and Applications, 2020
Rob Turner,1 Sean Robert Wevrett,1 Suzanne Edmunds,1 Marc B Brown,1,2 Robert Atkinson,3 Oluwajoba Adegoke,3 Anuradha Kulasekaran,4 Tim Shea5 1MedPharm Ltd, Surrey Research Park, Guildford, UK; 2The Research Centre in Topical Drug Delivery and Toxicology (
Turner R, Wevrett SR, Edmunds S, Brown MB, Atkinson R, Adegoke O, Kulasekaran A, Shea T   +7 more
doaj  

Ultra-High-Pressure Liquid Chromatography ☆ [PDF]

, 2017
One decade has passed since the introduction of commercial ultra-high-pressure liquid chromatography (UHPLC) technology and columns packed with sub-2-μm particles, which has led to significant improvements in separation efficiency and sample throughput. This article outlines fundamental and practical aspects of UHPLC.
Eeltink, Sebastiaan, De Vos, Jelle
openaire   +2 more sources

Model of the meniscus of an ionic liquid ion source. [PDF]

, 2008
A simple model of the transfer of charge and ion evaporation in the meniscus of an ionic-liquid ion source working in the purely ionic regime is proposed on the basis of order-of-magnitude estimates which show that, in this regime, _i_ the flow in the ...
C. Bartoli, F. J. Higuera, G. K. Batchelor, I. Guerrero, J. O. Bockris, J. O. Bockris, L. D. Landau, P. D. Prewett, R. F. Probstein   +8 more
core   +2 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Glass–liquid transition of water at high pressure [PDF]

Proceedings of the National Academy of Sciences, 2011
The knowledge of the existence of liquid water under extreme conditions and its concomitant properties are important in many fields of science. Glassy water has previously been prepared by hyperquenching micron-sized droplets of liquid water and vapor deposition on a cold substrate (ASW), and its transformation to an ultraviscous liquid ...
openaire   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Combination of Medium- and High-Pressure Liquid Chromatography for Isolation of L-tryptophan (Q-marker) from Medicago sativa Extract

Separations, 2022
Medicago sativa (alfalfa) is a widely used animal feed. However, its quality has been difficult to control due to the lack of appropriate marker compounds.
Shixuan Zhang, Yonggui Ma, Ronghua Ma, Qilan Wang, Jun Dang   +4 more
doaj   +1 more source

Compressible Air Entrapment in High-Speed Drop Impacts on Solid Surfaces

, 2012
Using high-speed photography coupled with optical interference, we experimentally study the air entrapment during a liquid drop impacting a solid substrate.
Liu, Yuan, Tan, Peng, Xu, Lei
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Occurrence and Exposure Assessment of Aflatoxin B1 and Ochratoxin A in Pearl Millet (Pennisetum glaucum L.) from Tunisia

Journal of Food Quality and Hazards Control, 2020
Background: Ochratoxin A (OTA) and Aflatoxin B1 (AFB1) are toxic secondary  metabolites produced by certain mold species. In this primarily survey, we examined the OTA and AFB1 contamination of pearl millet grains distributed in Tunisia.
S. Lasram, Z. Hamdi, A. Ghorbel
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