Results 81 to 90 of about 2,136,147 (266)
High step-up resonant push–pull converter with high efficiency
IET Power Electronics, 2009 A high-efficient current-fed push-pull converter is proposed for high output voltage applications supplied by low-voltage and high-current sources such as fuel cells and solar cells. The proposed converter conserves inherent advantages of a conventional current-fed push-pull converter such as low input current stress and high-voltage conversion ratio ...
Kim, EH, Kwon, BH
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
IEEE AccessAn interleaved Buck-Boost-Zeta converter with the coupled inductor multiplier cell and zero input current ripple is proposed in this paper, which is suitable for high step-up applications such as the photovoltaic generation system.
Ying He, Liang Chen, Xuanjin Sun
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
High-Performance Single Switch High Step-Up Quadratic DC-DC Converter With Switched Capacitor Cell
IEEE AccessThis article presents a single-switch high step-up quadratic DC-DC converter for DC microgrid applications. The quadratic boost converter is integrated with switched capacitor cell along with coupled inductor to achieve high gain at reduced duty ratio ...
D. V. Sudarsan Reddy +2 more
doaj +1 more source
Improved Quasi-Z-Source High Step-Up DC-DC Converter Based on Voltage-Doubler Topology. [PDF]
Sensors (Basel), 2022 Sai T, Moon Y, Sugimoto Y.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source