Results 101 to 110 of about 24,558,722 (248)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Improved Quasi-Z-Source High Step-Up DC-DC Converter Based on Voltage-Doubler Topology. [PDF]
Sai T, Moon Y, Sugimoto Y.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An interleaved Buck-Boost-Zeta converter with the coupled inductor multiplier cell and zero input current ripple is proposed in this paper, which is suitable for high step-up applications such as the photovoltaic generation system.
Ying He, Liang Chen, Xuanjin Sun
doaj +1 more source
High Step-Up Ratio DC-AC Converter Using Fourth-Order LCLC Resonant Circuit for Ultrasonic Fingerprint-Sensor Drivers. [PDF]
Liu W, Shi Y, Sun Z, Zhang L, Zhang Q.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Tapped-inductor bi-directional Cuk converter with high step-up/down conversion ratio and its optimum design. [PDF]
Chen H, Lin WM, Liu WR, He W.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
High-Performance Single Switch High Step-Up Quadratic DC-DC Converter With Switched Capacitor Cell
This article presents a single-switch high step-up quadratic DC-DC converter for DC microgrid applications. The quadratic boost converter is integrated with switched capacitor cell along with coupled inductor to achieve high gain at reduced duty ratio ...
D. V. Sudarsan Reddy +2 more
doaj +1 more source

