Results 111 to 120 of about 7,358,551 (300)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Shouji: A Fast and Efficient Pre-Alignment Filter for Sequence Alignment

open access: yes, 2019
Motivation: The ability to generate massive amounts of sequencing data continues to overwhelm the processing capability of existing algorithms and compute infrastructures.
Alkan, Can   +4 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Microresonator-based high-resolution gas spectroscopy

open access: yes, 2017
In recent years, microresonator-based optical frequency combs have created up opportunities for developing a spectroscopy laboratory on a chip due to its broadband emission and high comb power.
Gaeta, Alexander L.   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An Interleaved Buck-Boost-Zeta Converter With Coupled Inductor Multiplier Cell and Zero Input Current Ripple for High Step-Up Applications

open access: yesIEEE Access
An interleaved Buck-Boost-Zeta converter with the coupled inductor multiplier cell and zero input current ripple is proposed in this paper, which is suitable for high step-up applications such as the photovoltaic generation system.
Ying He, Liang Chen, Xuanjin Sun
doaj   +1 more source

Electrical and Magnetic behaviour of PrFeAsO0.8F0.2 superconductor

open access: yes, 2014
The superconducting and ground state samples of PrFeAsO0.8F0.2 and PrFeAsO have been synthesised via easy and versatile single step solid state reaction route.
Awana, V. P. S.   +4 more
core  

High Order Maximum Principle Preserving Semi-Lagrangian Finite Difference WENO schemes for the Vlasov Equation

open access: yes, 2014
In this paper, we propose the parametrized maximum principle preserving (MPP) flux limiter, originally developed in [Z. Xu, Math. Comp., (2013), in press], to the semi- Lagrangian finite difference weighted essentially non-oscillatory scheme for solving ...
Christlieb, Andrew   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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