Results 81 to 90 of about 22,401,602 (289)

Hybrid Multiport Converter for High Step-Up Renewable Energy Applications

, 2020
In this paper, a hybrid converter configuration is proposed suitable for high step-up renewable energy applications. The proposed topologies are derived by combining quadratic boost converter with Cuk and SEPIC converter.
Stepenko, Serhii, Nataraj Barath, J. G., A. Soundarrajan, Nataraj Barath J.G., Sanjeevikumar Padmanaban, Soundarrajan, A., Bondarenko, Oleksandr, Oleksandr Bondarenko, Padmanaban, Sanjeevikumar, Serhii Stepenko, Prystupa, Anatoliy, Anatoliy Prystupa   +11 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Bidirectional Step-Up/Step-Down DC-DC Converter with Magnetically Coupled Coils

, 2013
The paper is focused on bidirectional up/down DC-DC converter with magnetically coupled coils (MCC), which can be utilized as a part of power semiconductor system in traction, automotive, or industrial applications like renewable energy sources. Proposed
Giacomo Scelba, Branislav Dobrucky, Michal Frivaldsky, Pavol Spanik, Peter Drgona   +4 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

ZVT Interleaved High Step-Up Converter For Renewable Energy Systems

, 2023
ZVT Interleaved High Step-Up Converter For Renewable Energy ...
Baharak Akhlaghi (15201274), Dhananjay Thiruvady (13066857), Hosein Farzanehfard (15201277), Rasoul Faraji (15201280), Fatemeh Shiri (10579486)   +4 more
core   +1 more source

Design of Power/Analog/Digital Systems Through Mixed-Level Simulations [PDF]

, 2011
In recent years the development of the applications in the field of telecommunications, data processing, control, renewable energy generation, consumer and automotive electronics determined the need for increasingly complex systems, also in shorter time ...
Coppola, Marino
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

High Step-Up High-Efficiency Non-Isolated DC-DC Converter

, 2022
This paper studies a high step-up DC-DC converter, derived from the DC-DC voltage-fed push-pull converter, which main features are magnetic and electric symmetry of the internal transformer, transfer to the load of the energy trapped in the leakage ...
Ivo Barbi, Romero Leandro Andersen (13119475), Romero Leandro Andersen, Ivo Barbi (9198464)   +3 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source