Results 91 to 100 of about 2,568,150 (244)
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Decoherence of a quantum two-level system by spectral diffusion
, 2016 We study the dephasing of an individual high-frequency tunneling two-level system (TLS) due to its interaction with an ensemble of low-frequency thermal TLSs which are described by the standard tunneling model (STM).
Matityahu, Shlomi +3 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Pressure-strain-rate events in homogeneous turbulent shear flow [PDF]
A detailed study of the intercomponent energy transfer processes by the pressure-strain-rate in homogeneous turbulent shear flow is presented. Probability density functions (pdf's) and contour plots of the rapid and slow pressure-strain-rate show that ...
Brasseur, James G., Lee, Moon J.
core +1 more source
Very High Strain Rate Range [PDF]
, 2018 The classical Split Hopkinson Pressure Bar (SHPB) system is considered to be able to perform tests at strain rates ranging from 102 to 104s−1. However, some modifications can be carried out to extend the reachable strain rate within the specimen. The mean strain rate defined within the specimen:\[\dot{\varepsilon}_s =\frac{V_\text{out}-V_\text{in}}{l_s}
Heuzé, Thomas +2 more
openaire +3 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
High Strain Rate Deformation Behavior of Gradient Rolling AZ31 Alloys
MetalsA dynamic impact test was performed on as-rolled AZ31 alloys with gradient microstructure under various strains. The microstructural evolution and mechanical properties were systematically investigated.
Yingjie Li +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
High Strain Rate Response of Adhesively Bonded Fiber-Reinforced Composite Joints A Computational Study to Guide Experimental Design [PDF]
Adhesively bonded carbon fiber-reinforced epoxy composite laminates are widely used in aerospace applications. During a high energy impact event, these laminates are often subjected to high strain rate loading.
Justusson, Brian +5 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source