Results 81 to 90 of about 1,454,923 (313)

Modeling strain rate sensitivity and high temperature deformation of Mg-3Al-1Zn alloy

open access: yesJournal of Magnesium and Alloys, 2019
Increasing the plastic deformation temperature of Mg alloys results in higher strain rate sensitivity, easier activation of secondary slip modes, and impeded twinning. In this study, the strain rate sensitivity is estimated for each deformation mode, and
Adrien Chapuis, Qing Liu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Intermediate strain rate testing methodologies and full-field optical strain measurement techniques for composite materials characterisation

open access: yes, 2014
Two optical full-field strain measurement techniques, Digital Image Correlation and the Grid Method, are applied to characterise the strain-rate dependent constitutive behaviour of composite materials.
Longana, M.L.
core  

Constitutive Equations at High Strain Rates

open access: yes
4968In this review is presented which forms of semiempirical or physically-based constitutive equations are useful for high strain rate applications, how they match the real behavior, and where are the ...
Meyer, Lothar W.
core   +1 more source

Partial-mediated slips in nanocrystalline Ni at high strain rate

open access: yes, 2007
Previous experiments on nanocrystalline Ni were conducted under quasistatic strain rates (similar to 3x10(-3)/s), which are much lower than that used in typical molecular dynamics simulations (>3x10(7)/s), thus making direct comparison of modeling and ...
Qi Y   +3 more
core   +1 more source

Unveiling the dynamic mechanical behavior with phase-transformation and microstructural evolution in a novel dual-phase high-entropy alloy

open access: yesMaterials & Design
A novel TiZrHfTaMo refractory high-entropy alloy (RHEA) was developed by adding Molybdenum to the TiZrHfTa system to enhance its mechanical properties.
Muhammad Abubaker Khan   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Investigation of strain rate sensitivity of polymer matrix composites

open access: yes, 2004
Includes bibliographical references (leaves 210-219)An investigation into high strain rate behaviour of polymer composites was performed by developing a finite element model for a fibre reinforced polymer (FRP) plates impacted at varying strain rates ...
Ochola, Robert O
core  

Strain-rate-dependent microplane model for high-rate comminution of concrete under impact based on kinetic energy release theory

open access: yes, 2015
The apparent increase of strength of concrete at very high strain rates experienced in projectile impact (10 s(-1) to 10(6) s(-1)), called 'dynamic overstress', has recently been explained by the theory of release of local kinetic energy of shear strain ...
Kirane K   +3 more
core   +1 more source

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