Results 71 to 80 of about 1,454,923 (313)
High Strain Rate Compaction of Porous Materials – Experiments and Modelling
EPJ Web of Conferences, 2018 Porosity can be found in many forms in common materials, either naturally occurring such as wood, or introduced by a manufacturing process. Applications for such materials include impact protection and energy absorption, which require a good ...
Cotton Matthew, Maw John
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Characterisation and modelling of structural bonding at high strain rate
EPJ Web of Conferences, 2012 These paper deals with the development of new bonded joint modelling for crash application. A new testing device has been set up on Split Hopkinson bars in order to identify adhesive’s properties in assemblies for high strain rate and for different ...
Lesueur D. +5 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
High-strain-rate superplasticity in oxide ceramics
Science and Technology of Advanced Materials, 2007 Factors limiting the strain rate of superplastic deformation in ceramic materials are discussed on the basis of existing models and experimental results concerning high-temperature plastic deformation, intergranular cavitation and dynamic grain growth ...
Keijiro Hiraga, Byung-Nam Kim, Koji Morita, Hidehiro Yoshida, Tohru S. Suzuki and Yoshio Sakka
doaj
High strain rate tensile and compressive effects in glassy polymers
EPJ Web of Conferences, 2012 Polymers are increasingly used in impact and complex high rate loading applications. Generally, the mechanical response of glassy polymers under high strain rates has been determined in compression.
Woodworth B.T. +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2010 Traditionally high strain rate material characterisations have been conducted using strain gauges and/or cross head displacements in servo-hydraulic test machines, and force transducers in split Hopkinson bar experiments.
Syngellakis, Stavros +8 more
core
, 2013 Background: The production of bioethanol from lignocellulose hydrolysates requires a robust, D-xylose-fermenting and inhibitor-tolerant microorganism as catalyst.
Eckhard Boles +29 more
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