Results 41 to 50 of about 15,463,846 (249)
Protein synthesis rate is the predominant regulator of protein expression during differentiation
Molecular Systems Biology, 2013 External perturbations, by forcing cells to adapt to a new environment, often elicit large‐scale changes in gene expression resulting in an altered proteome that improves the cell's fitness in the new conditions.
Anders R Kristensen +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo
Frontiers in Pharmacology, 2018 Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes.
Sandra Kraljević Pavelić +6 more
doaj +1 more source
High-Throughput Analysis of the Plasma N-Glycome by UHPLC
, 2016 The understanding of glycosylation alterations in health and disease has evolved significantly and glycans are considered to be relevant biomarker candidates.
O’Flaherty, R. +9 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Metals, 2023 There is a huge demand for high-performance materials in extreme environments involving wear and corrosion. High chromium white cast irons (HCWCIs) display better performance than many materials since they are of sufficient hardness for wear protection ...
Simbarashe Fashu, Vera Trabadelo
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Cell Discovery, 2023 How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription.
Xinyu Zhang +7 more
doaj +1 more source
Next Generation High Throughput Satellite System [PDF]
, 2012 This paper aims at presenting an overview of the state-of-the-art in High Throughput Satellite (HTS) systems for Fixed Satellite Services (FSS) and High Density-FSS.
Vidal, Oriol +11 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source