Results 241 to 250 of about 242,782 (295)

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

High-throughput screening and characterization of novel inhibitors targeting HIV-1 protease precursor autoprocessing. [PDF]

Sci Rep
Jeep RH, Huang L, Ngo TA, Zeng FY, Boehlke J, Bennett L, Ashman S, Pass I, Chung TDY, Chen C.   +9 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Integrating computational simulation and high-throughput screening for the development of robust ultra-high concentration formulation of IgG1 antibody. [PDF]

MAbs
Lyu C, Lu S, Yin Y, Li H, Xing D, Lu Y, Zheng S, Zhang Q, Gao L, Xu S, Zou Q, Liu F, Zhang J, Kang Y.   +13 more
europepmc   +1 more source

LigHTS: Massively Parallel Biomimetic Photo-Functionalization for Imaging-Based Ultra-High-Throughput Screening

Enrico A, Rigolli S, Zimmermann J, Pezzotti M, Torchia E, Di Sante M, Auricchio F, Pasqualini FS.   +7 more
europepmc   +1 more source

Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening. [PDF]

SLAS Discov
Lin, Pearson LA, Ahmad S, O'Neill S, Post J, Robinson C, Scott DE, Gilbert IH.   +7 more
europepmc   +1 more source

High-Throughput Screening Tool to Identify Small Molecule Inhibitors of Telomerase. [PDF]

ACS Chem Biol
Aquilanti E, Barkho S, Bozinov V, Kageler L, Garrity-Janger M, Mesleh MF, Horner S, Ranaghan MJ, Meyerson M.   +8 more
europepmc   +1 more source

High-throughput screening identifies the activity of histone deacetylase inhibitors in patient-derived models of soft tissue sarcoma. [PDF]

Cancer Biol Ther
Danks MR, Manasterski PJ, Beetham H, Dawson JC, Elliott RJR, Culley J, Krishna R, Muir M, Thomson JP, Oswald AJ, Ewing A, Kerrison WGJ, Huang PH, Nixon I, Carragher NO, Brunton VG.   +15 more
europepmc   +1 more source