Results 111 to 120 of about 422,503 (299)

DMCpy: A powder and single crystal neutron diffraction software for the DMC diffractometer

SoftwareX
The recently upgraded DMC diffractometer at SINQ, Paul Scherrer Institute, Switzerland, equipped with a state-of-the-art 2D 3He detector, enables high-resolution neutron diffraction experiments optimized for both powder and single-crystal studies.
Jakob Lass, Samuel Harrison Moody, Øystein Slagtern Fjellvåg   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Real-time audio spectrum analysis and dynamic volume control system based on FFT

Egyptian Informatics Journal
Traditional sound mixers are often implemented using analog circuits, which have problems such as long response time and low adjustment accuracy. Therefore, this study designs a musical instrument tuning system based on Field Programmable Gate Array ...
Renjie Huang, Hongyang Huang
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Development and Application of Concentric Electric Downhole Measuring and Regulating Instrument

Shiyou jixie, 2016
To address the issues of multizone water injection in directional well like low success rate and efficiency of measuring and regulating and low precision of measuring and regulating small volume water injection,a concentric electric downhole measuring ...
Yu Jiuzheng, Ju Yafeng, Yang Lingzhi
doaj  

Thorium determination in seawater by inductively coupled plasma mass spectrometry: Method development and oceanographic applications

Talanta Open
Thorium isotopes in the ocean (including radiogenic isotopes and terrigenous-derived 232Th) serve as key tracers for studying land-derived material transport. While high-sensitivity and high-resolution inductively coupled plasma mass spectrometry (ICP-MS)
Yingjie Zou, Peng Wang, Lei Xu, Hong Ren, Yiyao Cao   +4 more
doaj   +1 more source

QUANTEYE: The Quantum optics instrument for OWL

, 2006
A brief description of the QuantEYE instrument proposed as a focal plane instrument for OWL is given. This instrument is dedicated to the very high speed observation of many active phenomena with a photon counting capability of up to 1GHz.
V. DA DEPPO, TAMBURINI, FABRIZIO, H. UTHAS, Fosbury, R.A.E., Da Deppo, V., BARBIERI, CESARE, NALETTO, GIAMPIERO, R. NILSSON, L. ZAMPIERI, R. A. E. FOSBURY, Uthas, Helena, D. DRAVINS, Barbieri, C., Dravins, Dainis, D'Onofrio, M., Naletto, G., Zampieri, L., Fornasier, S., Tamburini, F., Occhipinti, T., Nilsson, Ricky, T. OCCHIPINTI, D'ONOFRIO, MAURO, S. FORNASIER   +23 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source