Results 121 to 130 of about 422,503 (299)
工程科学与技术, 2007 :At present, the portable instruments for radon measurement are poor measurement sensitivity, large volume and high power consumption. On the basis of the passive indirect measurement method, Au-Si surface barrier detector, charge sensitive ...
doaj
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Spectrograph design for the Asgard/BIFROST spectro-interferometric instrument for the VLTI
, 2022 The BIFROST instrument will be the first VLTI instrument optimised for high spectral resolution up to R=25,000 and operate between 1.05 and 1.7 µm. A key component of the instrument will be the spectrograph, where we require a high throughput over a ...
M Frangiamore (21945299) +6 more
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
NHTSA - Behavioral Safety Research;Volpe National Transportation Systems Center, Technical Reference Centerhttps://doi.org/10.21949/15249021974PDFResearch PaperOates, John Francis, 1943-McCay, Robert T.Dunlap and Associates, inc.United States.
core
Innovative Airport and ATM Concept: (Operating an Endless Runway)
, 2013 This paper presents an innovative and radical new concept for future airport operations, consisting of an airport with one circular circumventing runway, called The Endless Runway.
Loth, Steffen +6 more
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Thermal design of the SPICA/ESI instrument
The ESI instrument (European SPICA Instrument) is a proposed imaging spectrometer for the 30-210μm band for the JAXA SPICA mission. The instrument will have unprecedented spatial resolution and sensitivity due to the large 03.5m telescope aperture, cold ...
Winter, Berend +5 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source