Results 101 to 110 of about 3,450,969 (293)
Finite Cell-Elements of Higher Order
, 2004 X. International Conference on Computing in Civil and Building Engineering: proceedings ; [ICCCBE], Weimar, June 02-04, 2004, vol ...
Milbradt, Peter +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Hierarchical tapered bar elements undergoing axial deformation [PDF]
A method is described to model the dynamics of tapered axial bars of various cross sections based on the well-known Craig/Bampton component mode synthesis technique.
Ganesan, N., Thampi, S. K.
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Numerical integration on GPUs for higher order finite elements
Computers & Mathematics with Applications, 2014 The paper considers the problem of implementation on graphics processors of numerical integration routines for higher order finite element approximations. The design of suitable GPU kernels is investigated in the context of general purpose integration procedures, as well as particular example applications.
Krzysztof Banas +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Separation of Plastic Particles in Electrostatic Field Produced by Electrodes of Optimized Shape
Communications, 2013 Shape optimization of electrodes for the device for electrostatic separation of triboelectrically charged plastic particles is carried out. The objective function maximizes the efficiency of separation consisting in the highest possible number of ...
Frantisek Mach +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Dynamics of flight of the fragments with higher order Haar wavelet method [PDF]
Proceedings of the Estonian Academy of SciencesFragments that have an irregular shape and move at high speeds are difficult to assess since experiments require high-tech solutions, and the differential equations that describe the motion cannot be solved analytically.
Lenart Kivistik +3 more
doaj +1 more source