Results 71 to 80 of about 18,656,673 (304)
Disagreement, Indirect Defeat, and Higher-Order Evidence [Elektronisk resurs]
, 2020 Some philosophers question whether higher-order evidence can support the radical skeptical conclusions that others take it to generate. Since disagreement is usually classified as being a type of higher-order evidence, these worries have in turn also ...
Tersman, Folke,, Risberg, Olle,
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hybrid volume completion with higher-order Bézier elements [PDF]
Computer Aided Geometric Design, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Suqin Zeng, Elaine Cohen
openaire +2 more sources
Disagreement, Indirect Defeat, and Higher-Order Evidence
, 2020 Some philosophers question whether higher-order evidence can support the radical skeptical conclusions that others take it to generate. Since disagreement is usually classified as being a type of higher-order evidence, these worries have in turn also ...
Risberg, Olle, Tersman, Folke
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Using situated learning and multimedia to investigate higher-order thinking [PDF]
, 1999 This paper describes a qualitative study into students' use of higher-order thinking as they use an interactive multimedia program based on a situated learning framework.
Oliver, R., Herrington, J.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
HOT [Higher Order Thinking Network newsletter]. #1. 2013: Spring.
, 2013 Quarterly; Began with issue 01 (spring 2013).; Newsletter of the Higher Order Thinking Schools Network.; Harvested from the web on 3/11 ...
Higher Order Thinking Schools Network (Conn.),
core +1 more source
Polynomial Approximation over Arbitrary Shape Domains
Mathematical and Computational ApplicationsIn spectral/finite element methods, a robust and stable high-order polynomial approximation method for the solution can significantly reduce the required number of degrees of freedom (DOFs) to achieve a certain level of accuracy.
Mohammad J. Mahtabi +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source