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HOT [Higher Order Thinking Network newsletter]. #2. 2013: Summer.
Quarterly; Began with issue 01 (spring 2013).; Newsletter of the Higher Order Thinking Schools Network.; Harvested from the web on 3/11 ...
Higher Order Thinking Schools Network (Conn.),
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
With the help of theoretical analysis and numerical simulation, the modal parameters of the two-dimensionally low-order beam elements and high-order beam elements based on the absolute nodal coordinate formulation were studied. The analytical solution of
ZHOU Chuan +4 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Higher-order + Polymorphic = Reusable [PDF]
This paper explores how certain ideas in object oriented languages have their correspondents in functional languages. In particular we look at the analogue of the iterators of the C++ standard template library.
Thompson, Simon
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Short-flow-time expansion of quark bilinears through next-to-next-to-leading order QCD
The gradient-flow formalism proves to be a useful tool in lattice calculations of quantum chromodynamics. For example, it can be used as a scheme to renormalize composite operators by inverting the short-flow-time expansion of the corresponding flowed ...
Janosch Borgulat +3 more
doaj +1 more source
Best theory diagrams for multilayered structures via shell finite elements
Composite structures are convenient structural solutions for many engineering fields, but their design is challenging and may lead to oversizing due to the significant amount of uncertainties concerning the current modeling capabilities.
Marco Petrolo, Erasmo Carrera
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Higher-order boundary infinite elements
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Harari, Isaac +2 more
openaire +2 more sources

