Results 91 to 100 of about 1,243,157 (307)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Application of Mass Lumped Higher Order Finite Elements [PDF]
, 2005 There are many interesting phenomena in extended-MHD such as anisotropic transport, mhd, 2-fluid effects stellarator and hot particles. Any one of them challenges numerical analysts, and researchers are seeking for higher order methods, such as higher ...
J. Chen, H.R. Strauss, S.C. Jardin, W. Park, L.E. Sugiyama, G. Fu, J. Breslau
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A method for creating a class of triangular C1 finite elements
, 2011 Finite elements providing a C1 continuous interpolation are useful in the numerical solution of problems where the underlying partial differential equation is of fourth order, such as beam and plate bending and deformation of strain-gradient-dependent ...
A. Zervos +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The Scientific World Journal, 2014 The high-order layerwise element models have been used for damaged plates and shells in the presence of singularities such as crack, cutout, and delamination.
Jae S. Ahn, Seung H. Yang, Kwang S. Woo
doaj +1 more source
Advanced Modeling and Simulation in Engineering Sciences, 2019 Shear and membrane locking phenomena are fundamental issues of shell finite element models. A family of refined shell elements for laminated structures has been developed in the framework of Carrera Unified Formulation, including hierarchical elements ...
Guohong Li +6 more
doaj +1 more source
Numerical integration on GPUs for higher order finite elements
Computers & Mathematics with Applications, 2014 The paper considers the problem of implementation on graphics processors of numerical integration routines for higher order finite element approximations. The design of suitable GPU kernels is investigated in the context of general purpose integration procedures, as well as particular example applications.
Krzysztof Banas +2 more
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Ocular higher-order aberrations and visual performance [PDF]
, 2011 Since adaptive optics was first used to correct the monochromatic aberrations of the eye over a decade ago there has been considerable interest in correcting the ocular aberrations beyond defocus and astigmatism.
Young, Laura Kate, YOUNG, LAURA,KATE
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