Results 71 to 80 of about 1,734,631 (265)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
HIGHER-ORDER CURVATURE TERMS IN BORN–INFELD TYPE BRANE THEORIES [PDF]
International Journal of Modern Physics D, 2011 The field equations associated to Born–Infeld type brane theories are studied by using auxiliary variables. This approach hinges on the fact, that the expressions defining the physical and geometrical quantities describing the worldvolume are varied independently.
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Results in Physics, 2019 In this work, soliton solutions of higher order non-linear Schrödinger equation (NLSE) with derivative non-Kerr non-linear terms are constructed by employing two analytical techniques, namely, exp(-Φ(ζ))-expansion and improved simple equation methods ...
Muhammad Arshad +2 more
doaj +1 more source
The marginality principle revisited: Should "higher-order" terms always be accompanied by "lower-order" terms in regression analyses? [PDF]
Biom J, 2023 Morris TP, van Smeden M, Pham TM.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Higher Order Terms in Multiscale Expansions: A Linearized KdV Hierarchy [PDF]
Journal of Nonlinear Mathematical Physics, 2002 We consider a wide class of model equations, able to describe wave propagation in dispersive nonlinear media. The Korteweg-de Vries (KdV) equation is derived in this general frame under some conditions, the physical meanings of which are clarified. It is obtained as usual at leading order in some multiscale expansion.
openaire +3 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Thermodynamics of Electrolytes.: V. Effects of Higher-Order Electrostatic Terms [PDF]
Journal of Solution Chemistry, 1975 The contribution of higher-order electrostatic terms (beyond the Debye-Huckel approximation) to the thermodynamic properties of mixed and pure electrolytes is investigated. It is found that these effects are important for cases of unsymmetrical mixing, especially when one ion has a charge of three units or more.
openaire +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source