Results 51 to 60 of about 1,148,463 (303)

Engineering strategy of yeast metabolism for higher alcohol production

Microbial Cell Factories, 2011
Background While Saccharomyces cerevisiae is a promising host for cost-effective biorefinary processes due to its tolerance to various stresses during fermentation, the metabolically engineered S. cerevisiae strains exhibited rather limited production of
Shimizu Hiroshi, Ishii Jun, Kondo Takashi, Furusawa Chikara, Matsuda Fumio, Kondo Akihiko   +5 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Reading Motivation, Alcohol and Drug Use in Future Teachers in Preschool and Primary School

European Journal of Investigation in Health, Psychology and Education, 2020
Future teachers will have to develop the reading habit in their students, as this is an essential factor in schoolchildren. The lack of reading motivation among young people and the need to have it in order to transmit it has been evidenced. Young people
María de la Rocha Díaz, Inmaculada Méndez, Cecilia Ruiz-Esteban   +2 more
doaj   +1 more source

An international comparison of gender differences in mental health among higher-education students during the first wave of the COVID-19 pandemic: a multilevel design

Archives of Public Health, 2023
Background Mental health problems are a common phenomenon among higher-education students. How these mental health problems manifest themselves appears to differ between male and female students.
Sarah Van de Velde, Anneleen De Cuyper, Leen De Kort, Kimberly Jacobs, Nikoletta Somogyi, Robert Tholen, Nina Van Eekert, Veerle Buffel   +7 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Effective alcohol policies and lifetime abstinence: An analysis of the International Alcohol Control policy index

, 2023
© 2022 The Authors.Introduction Alcohol abstinence remains common among adults globally, although low and middle-income countries are experiencing declines in abstention. The effect of alcohol policies on lifetime abstinence is poorly understood.
Harker N, Leung J, van Dalen W, Paraje G, Randerson S, Callinan S, Pham C, Gordon R, Williams PP, Schelleman-Offermans K, Huckle T, Casswell S, Torun P, Parker K, Sengee G, Byron K, Graydon-Guy T, Parry CD, MacKintosh AM, Romeo J, Chaiyasong S, Meier P   +21 more
core   +1 more source

Prospective study of exposure to smoking imagery in films and changes in susceptibility to smoking in a cohort of school students in Southern India

Tobacco Induced Diseases
Introduction India has unique tobacco-free film and TV rules designed to prevent tobacco uptake. In this study, we examined the potential influence of exposure to smoking imagery in regionally famous films, on susceptibility to smoke in teenagers ...
Veena G. Kamath, Muralidhar M. Kulkarni, Asha Kamath, Sarah Lewis, Ilze Bogdanovica, Manpreet Bains, Jo Cranwell, Andrew Fogarty, Monika Arora, Deepika Bahl, Gaurang P. Nazar, Ashwath K. Naik, Kirtinath Ballal, Rohith Bhagawath, John Britton   +14 more
doaj   +1 more source

The Influence of Gut Dysbiosis in the Pathogenesis and Management of Ischemic Stroke

Cells, 2022
Recent research on the gut microbiome has revealed the influence of gut microbiota (GM) on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity, abundance, and functions of the gut microbiome, termed gut dysbiosis, results in
Saravana Babu Chidambaram, Annan Gopinath Rathipriya, Arehally M. Mahalakshmi, Sonali Sharma, Tousif Ahmed Hediyal, Bipul Ray, Tuladhar Sunanda, Wiramon Rungratanawanich, Rajpal Singh Kashyap, M. Walid Qoronfleh, Musthafa Mohamed Essa, Byoung-Joon Song, Tanya M. Monaghan   +12 more
doaj   +1 more source