Results 61 to 70 of about 6,302,443 (314)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

La division du travail enseignant et ses effets sur les savoirs enseignés

open access: yesRecherches en Éducation, 2017
In high schools and at university, how do teachers to distribute classes and teachings among themselves? I am interested in an aspect of the division of teaching work, the distribution of services, but also to the results of this division on the ...
Marie David
doaj   +1 more source

Higher Education Outcomes, Graduate Employment and University Performance Indicators [PDF]

open access: yes
Official employment-related Performance Indicators in UK Higher Education are based on the population of students responding to the First Destination Supplement (FDS).
Bratti, Massimiliano   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The University Library and the development of higher education

open access: yesBiblios, 2013
The article refers to the importance of the university library for Higher Education as a greater source of knowledge. It also deals with the tasks that have been carried out in this institution since its foundation in the XII century up to now.
Ana Luisa Figueredo Figueredo   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Educational Technologists, Universal Design and Transforming Higher Education

open access: yesASCILITE Publications, 2019
The field of educational technology continues to develop and grow in an era of unprecedented demand for the fruits of the higher education orchard. However, the persistent inequalities in relation to access and transfer opportunities remain. In parallel the field of universal design has evolved as a framework that allows us to reframe the ambition of ...
openaire   +1 more source

Popularization in the Higher Education and Optimal Educational Policies [PDF]

open access: yes, 2000
In this paper, we construct a model which explains a change in demand for education, considering an individual preference for the higher education (university).
Furumatsu, Noriko
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The Contribution of Open and Distance Education to Higher Education in China

open access: yesOpen Praxis
Open and distance education (ODE) has played a key role in contributing to the growth of Chinese higher education (HE) ever since the mid-1950s.
Junhong Xiao, Asha Kanwar, Ruo Du
doaj   +1 more source

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