Results 111 to 120 of about 2,300,710 (317)

Higher education institutions, regional labour markets and population development [PDF]

open access: yes
An important motivation to establish and develop higher education institutions across regions is to improve and restructure the regional labour markets toward higher education jobs, contribute to maintain the regional settlement patterns of the ...
Lasse Sigbjørn Stambøl
core  

The impact of FE / HE mergers : interim findings [PDF]

open access: yes, 2002
"This paper outlines the results of an analysis of the curriculum offer and student numbers at former further education colleges who have transferred to the higher education sector following mergers with higher education institutions.
Craig, David, Sawbridge, Steve
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Higher Education Collaboratives for Community Engagement and Improvement [PDF]

open access: yes, 2005
Our society is in a period of dramatic change with the transition from an industrial-based to a knowledge-based economy, as well as technological advances, fiscal challenges of higher education, and cultural shifts in society as a whole.
Bowman, Nick   +4 more
core   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

High-sensitivity qPCR detection method based on silver flower-like LSPR-active material

open access: yesScientific Reports
Quantitative polymerase chain reaction (qPCR) technology offers advantages such as easy operation and high specificity, but also faces issues like lengthy detection time and low sensitivity.
Congxi Song   +9 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis

open access: yesJournal of Translational Medicine
Background Photon radiation has been shown to stimulate the secretion of radioresistant factors from tumor cells, ultimately promoting tumor angiogenesis and metastasis.
Hao Huang   +9 more
doaj   +1 more source

Educational Management in Higher Education Institutions:

open access: yesCadernos de Educação Tecnologia e Sociedade
Adequate quality and competitiveness management strategies in universities and other higher education institutions require a balanced approach to educational management. It involves setting clear goals and objectives, developing a system for monitoring and evaluating the quality of teaching and research activities, and continuously improving the ...
Illia Lysokon   +4 more
openaire   +1 more source

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