Results 91 to 100 of about 15,910,979 (247)

Higher Education Funding Study Council report

, 2006
Title from cover of PDF document (viewed July 3, 2006).; "May 2006."; Harvested from the web on 7/5/06[Topics:] Student focus/access/retention/affordability -- Operational and administrative efficiencies -- Workforce and economic development ...
Ohio. Higher Education Funding Study Council., Higher Education Funding Study Council.   +1 more
core  

CO2-responsive terpolymer hydrogels with adjustable dynamic networks for fractured plugging in the reservoir

Scientific Reports
To address the limitations of conventional CO₂-responsive plugging materials (fixed network structure, slow response, and poor long-term stability) in fractured reservoirs, a novel terpolymer hydrogel poly(acrylamide-co-2-acrylamido-2-methylpropane ...
Yuanzi Yan, Yan Tao, Shaoli Zhou, Yunfeng Fan, Peng Zhang   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

eEF2K as an important kinase associated with cancer survival and prognosis

Scientific Reports
Eukaryotic Elongation Factor 2 Kinase (eEF2K), a member of the α-kinase family, services as a crucial negative regulator of protein synthesis, particularly under conditions of cellular stress.
Nan Wang, Li-Lan Cen, Zhe Tian, Miao-Miao An, Qian Gu, Xin-Hong Zhou, Yi-He Zhang, Lucas Liu, Jun Zhang, Di Yang, Yong-Zhi Huang, Xi-Dai Long, Qian Yang   +12 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Report of the Higher Education Subcommittee : Reopen Connecticut

, 2020
1 online resource (16 pages)Corrected version--May 8 ...
Reopen Connecticut (Initiative). Higher Education Subcommittee, author
core  

Pressure-Modulated Interphase Boundary Formation Feasibility, Band Alignment, and Optoelectronic Performance in CsPbI₃

Photonics
CsPbI3 exhibits multiple crystal phases, and the kinetic barriers for phase transitions are relatively low, facilitating the formation of abundant interphase boundaries (IBs) during phase transitions.
Xinyu Shi, Chenhao Liu, Xinyi Zang, Ying Wang, Huanjun Lu, Can Huang, Gaoyuan Chen, Chunlan Ma   +7 more
doaj   +1 more source